PCL-PEG copolymer based injectable thermosensitive hydrogels
A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …
applications in the last few decades because of their excellent biodegradability and …
Bispecific antibodies: a mechanistic review of the pipeline
AF Labrijn, ML Janmaat, JM Reichert… - Nature reviews Drug …, 2019 - nature.com
The term bispecific antibody (bsAb) is used to describe a large family of molecules designed
to recognize two different epitopes or antigens. BsAbs come in many formats, ranging from …
to recognize two different epitopes or antigens. BsAbs come in many formats, ranging from …
Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …
application in a rational manner depends on reliable, clinically applicable methods for …
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Challenges in clinical development of mesenchymal stromal/stem cells: concise review
I Mastrolia, EM Foppiani, A Murgia… - Stem cells …, 2019 - academic.oup.com
Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …
substantial interest among the scientific community because of their differentiation plasticity …
Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges
L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …
function and reduces scar. These effects occur via stimulation of endogenous repair …
Regenerative abilities of mesenchymal stem cells through mitochondrial transfer
The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …
Intra‐articular injection of mesenchymal stem cells for the treatment of osteoarthritis of the knee: a proof‐of‐concept clinical trial
CH Jo, YG Lee, WH Shin, H Kim, JW Chai… - Stem …, 2014 - academic.oup.com
Mesenchymal stem cells (MSCs) are known to have a potential for articular cartilage
regeneration. However, most studies focused on focal cartilage defect through surgical …
regeneration. However, most studies focused on focal cartilage defect through surgical …
Hypoxia inducible factor-1α potentiates jagged 1-mediated angiogenesis by mesenchymal stem cell-derived exosomes
H Gonzalez-King, NA García, I Ontoria-Oviedo… - Stem …, 2017 - academic.oup.com
Insufficient vessel growth associated with ischemia remains an unresolved issue in vascular
medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a …
medicine. Mesenchymal stem cells (MSCs) have been shown to promote angiogenesis via a …