This paper presents a biopsychological theory of drug addiction, the 'Incentive-Sensitization
Theory'. The theory addresses three fundamental questions. The first is: why do addicts …

Tolerance and sensitization are relatively simple manifestations of learning and memory that
refer to decreases and increases in the strength of a response to a stimulus induced by past …

Rationale The way an individual responds to cues associated with rewards may be a key
determinant of vulnerability to compulsive behavioral disorders. Objectives We studied …

The author presents a selective and integrative overview of cur-rent research examining
acute effects of abused drugs on aspects of behavioral control in humans. The review …

Substance abuse among schizophrenic patients is an increasingly recognized clinical
phenomenon. The authors review experimental and observed clinical effects of drug abuse …

When a discrete cue (a “sign”) is presented repeatedly in anticipation of a food reward the
cue can become imbued with incentive salience, leading some animals to approach and …

ROBINSON, TE, KE BROWMAN, HS CROMBAG, A. BADIANI. Modulation of the induction or
expression of pyschostimulant sensitization by the circumstances surrounding drug …

We have shown recently that the psychomotor activating effects of amphetamine in the rat
are much greater when this drug is administered in association with environmental novelty …

Repeated administrations of addictive drugs produce long-lasting changes in brain and
behavior. However, drug-induced neurobehavioral plasticity is not a mere function of the …

This book provides readers with the first survey of social conditions since the opening of the
borders between China and mainland Southeast Asia in the early 1990s. There have been …