Lipids and the ocular lens

D Borchman, MC Yappert - Journal of lipid research, 2010 - ASBMB
The unusually high levels of saturation and thus order contribute to the uniqueness of
human lens membranes. In addition, and unlike in most biomembranes, most of the lens …

How does oxygen diffuse from capillaries to tissue mitochondria? Barriers and pathways

SC Pias - The Journal of Physiology, 2021 - Wiley Online Library
Timely delivery of oxygen (O2) to tissue mitochondria is so essential that elaborate
circulatory systems have evolved to minimize diffusion distances within tissue. Yet …

[图书][B] Carotenoids: physical, chemical, and biological functions and properties

JT Landrum - 2009 - taylorfrancis.com
Carotenoids are of great interest due to their essential biological functions in both plants and
animals. However, the properties and functions of carotenoids in natural systems are …

[HTML][HTML] Oxygen permeability of the lipid bilayer membrane made of calf lens lipids

J Widomska, M Raguz, WK Subczynski - Biochimica et Biophysica Acta …, 2007 - Elsevier
The oxygen permeability coefficient across the membrane made of the total lipid extract from
the plasma membrane of calf lens was estimated from the profile of the oxygen transport …

Influence of cholesterol on the oxygen permeability of membranes: insight from atomistic simulations

RJ Dotson, CR Smith, K Bueche, G Angles, SC Pias - Biophysical journal, 2017 - cell.com
Cholesterol is widely known to alter the physical properties and permeability of membranes.
Several prior works have implicated cell membrane cholesterol as a barrier to tissue …

A 13C‐Labeled Triarylmethyl Radical as an EPR Spin Probe Highly Sensitive to Molecular Tumbling

M Poncelet, B Driesschaert - Angewandte Chemie, 2020 - Wiley Online Library
A stable triarylmethyl spin probe whose electron paramagnetic resonance (EPR) spectrum is
highly sensitive to molecular tumbling is reported. The strong anisotropy of the hyperfine …

Functions of cholesterol and the cholesterol bilayer domain specific to the fiber-cell plasma membrane of the eye lens

WK Subczynski, M Raguz, J Widomska… - The Journal of …, 2012 - Springer
The most unique feature of the eye lens fiber-cell plasma membrane is its extremely high
cholesterol content. Cholesterol saturates the bulk phospholipid bilayer and induces …

The water permeability of lens aquaporin-0 depends on its lipid bilayer environment

J Tong, JT Canty, MM Briggs, TJ McIntosh - Experimental eye research, 2013 - Elsevier
Abstract Aquaporin-0 (AQP0), the primary water channel in lens fiber cells, is critical to lens
development, organization, and function. In the avascular lens there is thought to be an …

Whales, lifespan, phospholipids, and cataracts [S]

D Borchman, R Stimmelmayr, JC George - Journal of Lipid Research, 2017 - ASBMB
This study addresses the question: why do rats get cataracts at 2 years, dogs at 8 years, and
whales do not develop cataracts for 200 years? Whale lens lipid phase transitions were …

Physical properties of lipid bilayers from EPR spin labeling and their influence on chemical reactions in a membrane environment

WK Subczynski, J Widomska, JB Feix - Free Radical Biology and Medicine, 2009 - Elsevier
The influence of a variety of microenvironmental factors on the inherent reactivity of
membrane-located reagents is poorly understood. A goal of this review is to provide detailed …