Antigen-presenting dendritic cells often acquire foreign antigens in peripheral tissues such
as the skin. Optimal encounter with naive T cells for the presentation of these antigens …

Vestweber, Dietmar, and James E. Blanks. Mechanisms That Regulate the Function of the
Selectins and Their Ligands. Physiol. Rev. 79: 181–213, 1999.—Selectins are a family of …

Dendritic cells (DCs) in lymphoid tissue arise from precursors that also produce monocytes
and plasmacytoid DCs (pDCs). Where DC and monocyte lineage commitment occurs and …

It is commonly believed that only T lymphocytes and B lymphocytes expressing
recombination-dependent antigen-specific receptors mediate contact hypersensitivity …

Secondary lymphoid organ chemokine (SLC) is expressed in high endothelial venules and
in T cell zones of spleen and lymph nodes (LNs) and strongly attracts naive T cells. In mice …

▪ Abstract Immunological memory can be defined as the faster and stronger response of an
animal that follows reexposure to the same antigen. By this definition, it is an operational …

It has been proposed that two different antigen-experienced T cell subsets may be
distinguishable by their preferential ability to home to lymphoid organs (central memory …

Heparin has been used clinically as an anticoagulant and antithrombotic agent for over 60
years. Here we show that the potent anti-inflammatory property of heparin results primarily …

To characterize the adhesion cascade that directs lymphocyte homing to peripheral lymph
nodes (PLNs), we investigated the molecular mechanisms of lymphocyte interactions with …

Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role
in immune defense against viral and bacterial infections and malignancies. NK cells are …