Mitogen-activated protein kinases (MAPKs) and enteric bacterial pathogens: a Complex Interplay

I Nandi, B Aroeti - International Journal of Molecular Sciences, 2023 - mdpi.com
Diverse extracellular and intracellular cues activate mammalian mitogen-activated protein
kinases (MAPKs). Canonically, the activation starts at cell surface receptors and continues …

Enteropathogenic Escherichia coli regulates host-cell mitochondrial morphology

JL Roxas, S Ramamurthy, K Cocchi, I Rutins… - Gut …, 2022 - Taylor & Francis
The diarrheagenic pathogen enteropathogenic Escherichia coli is responsible for significant
childhood mortality and morbidity. EPEC and related attaching-and-effacing (A/E) pathogens …

Enteropathogenic E. coli infection co-elicits lysosomal exocytosis and lytic host cell death

R Shtuhin-Rahav, A Olender, E Zlotkin-Rivkin… - Mbio, 2023 - Am Soc Microbiol
Enteropathogenic Escherichia coli (EPEC) is a primary human enteric bacterial pathogen
causing acute diarrhea in children. EPEC colonizes the small intestine, and the disease is …

EspH utilizes phosphoinositide and Rab binding domains to interact with plasma membrane infection sites and Rab GTPases

I Nandi, RP Ramachandran, DE Shalev… - Gut …, 2024 - Taylor & Francis
Enteropathogenic E. coli (EPEC) is a Gram-negative bacterial pathogen that causes
persistent diarrhea. Upon attachment to the apical plasma membrane of the intestinal …

Attaching and effacing pathogens modulate host mitochondrial structure and function

A Harishankar, VK Viswanathan - … Review of Cell and Molecular Biology, 2023 - Elsevier
Enteropathogenic and enterohemorrhagic Escherichia coli (EPEC and EHEC) are human
enteric pathogens that contribute significantly to morbidity and mortality worldwide. These …