[HTML][HTML] Advances in nanomaterials for the diagnosis and treatment of head and neck cancers: A review
C Yu, L Li, S Wang, Y Xu, L Wang, Y Huang, A Hieawy… - Bioactive Materials, 2023 - Elsevier
Nanomaterials (NMs) have increasingly been used for the diagnosis and treatment of head
and neck cancers (HNCs) over the past decade. HNCs can easily infiltrate surrounding …
and neck cancers (HNCs) over the past decade. HNCs can easily infiltrate surrounding …
Spotlight on photoactivatable liposomes beyond drug delivery: an enabler of multitargeting of molecular pathways
The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …
photochemical processes, has long been realized in the form of photodynamic therapy …
Remediating desmoplasia with EGFR‐targeted photoactivable multi‐inhibitor liposomes doubles overall survival in pancreatic cancer
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …
PD‐L1 Immune Checkpoint Targeted Photoactivable Liposomes (iTPALs) Prime the Stroma of Pancreatic Tumors and Promote Self‐Delivery
Desmoplasia in pancreatic ductal adenocarcinoma (PDAC) limits the penetration and
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
A single photodynamic priming protocol augments delivery of⍺‐PD‐L 1 m A bs and induces immunogenic cell death in head and neck tumors
C Bhandari, A Moffat, J Fakhry… - Photochemistry and …, 2023 - Wiley Online Library
Photodynamic priming (PDP) leverages the photobiological effects of subtherapeutic
photodynamic therapy (PDT) regimens to modulate the tumor vasculature and stroma. PDP …
photodynamic therapy (PDT) regimens to modulate the tumor vasculature and stroma. PDP …
Towards photodynamic image-guided surgery of head and neck tumors: photodynamic priming improves delivery and diagnostic accuracy of cetuximab-IRDye800CW
Fluorescence image-guided surgery (IGS) using antibody conjugates of the fluorophore
IRDye800CW have revolutionized the surgical debulking of tumors. Cetuximab, an anti …
IRDye800CW have revolutionized the surgical debulking of tumors. Cetuximab, an anti …
Enabling in vivo optical imaging of an osmium photosensitizer by micellar formulation
Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption,
favoring PDT activity at greater tissue depths. We recently reported on a potent Os (II) PS …
favoring PDT activity at greater tissue depths. We recently reported on a potent Os (II) PS …
Increasing the Dye Payload of Cetuximab-IRDye800CW Enables Photodynamic Therapy
A Nguyen, C Bhandari, M Keown… - Molecular …, 2024 - ACS Publications
Cetuximab (Cet)-IRDye800CW, among other antibody-IRDye800CW conjugates, is a
potentially effective tool for delineating tumor margins during fluorescence image-guided …
potentially effective tool for delineating tumor margins during fluorescence image-guided …
Development of an endoscopic auto-fluorescent sensing device to aid in the detection of breast cancer and inform photodynamic therapy
Breast cancer is the most diagnosed cancer type in women, with it being the second most
deadly cancer in terms of total yearly mortality. Due to the prevalence of this disease, better …
deadly cancer in terms of total yearly mortality. Due to the prevalence of this disease, better …
Spontaneous Transfer of Indocyanine Green from Liposomes to Albumin Is Inhibited by the Antioxidant α-Tocopherol
Indocyanine Green (ICG) is a clinically approved organic dye with near-infrared absorption
and fluorescence. Over the years, many efforts to improve the photophysical and …
and fluorescence. Over the years, many efforts to improve the photophysical and …