Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

Abstract The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …

As interest in γδ T cells grows rapidly, what key points are emerging, and where is caution
warranted? γδ T cells fulfill critical functions, as reflected in associations with vaccine …

Epithelial and mucosal barriers are critical interfaces physically separating the body from the
outside environment and are the tissues most exposed to microorganisms and potential …

Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

The contributions of γδ T cells to immune (patho) physiology in many pre‐clinical mouse
models have been associated with their rapid and abundant provision of two critical …

Inflammatory bowel disease (IBD) spans a range of chronic conditions affecting the
gastrointestinal (GI) tract, which are marked by intermittent flare-ups and remissions. IBD …

Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine
glands of the body, prevalently lacrimal and salivary glands. The pSS pathogenesis has …

T-lymphocytes (T cells) play a major role in adaptive immunity and current immune
checkpoint inhibitor-based cancer treatments. The regulation of their function is complex …

Background: Rheumatoid arthritis is a long-lasting inflammatory disease that usually
involves joints, but it can also affect other organs, including the skin and lungs. In this case, it …