[HTML][HTML] Radiosensitization and radioprotection by curcumin in glioblastoma and other cancers

V Zoi, V Galani, P Tsekeris, AP Kyritsis, GA Alexiou - Biomedicines, 2022 - mdpi.com
Radiation therapy plays an important role in almost every cancer treatment. However,
radiation toxicity to normal tissues, mainly due to the generation of reactive free radicals, has …

[HTML][HTML] Natural products for the immunotherapy of glioma

Q Huang, X Pan, W Zhu, W Zhao, H Xu, K Hu - Nutrients, 2023 - mdpi.com
Glioma immunotherapy has attracted increasing attention since the immune system plays a
vital role in suppressing tumor growth. Immunotherapy strategies are already being tested in …

The synergistic effects of betanin and radiotherapy in a prostate cancer cell line: an in vitro study

S Montazersaheb, S Jafari, MD Aytemir… - Molecular Biology …, 2023 - Springer
Background Prostate cancer is among the most common cancers in men with an increasing
incidence rate. Radiation therapy (RT) is a therapeutic strategy for the management of …

[HTML][HTML] Abrogation of cellular senescence induced by temozolomide in glioblastoma cells: search for senolytics

L Beltzig, M Christmann, B Kaina - Cells, 2022 - mdpi.com
A first-line therapeutic for high-grade glioma, notably glioblastoma (GBM), is the DNA
methylating drug temozolomide (TMZ). Previously, we showed that TMZ induces not only …

Review on the therapeutic potential of curcumin and its derivatives on glioma biology

M Mohamadian, SS Ahmadi, A Bahrami… - Neurochemical …, 2022 - Springer
Gliomas are common and aggressive brain tumors that carry a poor prognosis. The current
multimodal therapeutic option for glioma includes surgery subsequently temozolomide …

Synergistic effect of chrysin and radiotherapy against triple-negative breast cancer (TNBC) cell lines

S Jafari, S Dabiri, E Mehdizadeh Aghdam… - Clinical and …, 2023 - Springer
Purpose Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer,
accounting for 20% of cases. Due to the lack of a molecular target, limited options are …

[HTML][HTML] Natural plant compounds: does caffeine, dipotassium glycyrrhizinate, curcumin, and euphol play roles as antitumoral compounds in glioblastoma cell lines?

GA Bonafé, MN Boschiero, AR Sodré… - Frontiers in …, 2022 - frontiersin.org
Many plant-derived compounds are shown to be promising antitumor therapeutic agents by
enhancing apoptosis-related pathways and cell cycle impairment in tumor cells, including …

[HTML][HTML] Toxicity Evaluation and Controlled-Release of Curcumin-Loaded Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles: In Vitro and In Vivo Models

AL Luss, DV Bagrov, AV Yagolovich, EV Kukovyakina… - Pharmaceutics, 2023 - mdpi.com
Curcumin attracts huge attention because of its biological properties: it is antiproliferative,
antioxidant, anti-inflammatory, immunomodulatory and so on. However, its usage has been …

[HTML][HTML] Small molecules and immunotherapy agents for enhancing radiotherapy in glioblastoma

JK Matsui, HK Perlow, AR Ritter, R Upadhyay… - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is an aggressive primary brain tumor that is associated with a poor
prognosis and quality of life. The standard of care has changed minimally over the past two …

Chemical profiling, in vitro biological activities and Pearson correlation between chemical profiling and anticancer activities of four Abies species from Turkey

AS Yaglioglu, MS Yaglioglu, N Tosyalıoglu… - South African Journal of …, 2022 - Elsevier
Abies species are known to have various bioactive compounds and pharmacological
activities. In the manuscript, their bioactive components and anticancer activities of four …