Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling mediates
almost all immune regulatory processes, including those that are involved in tumor cell …

Interferon-gamma (IFN-c) is a cytokine that plays an important role in inducing and
modulating an array of immune responses. Cellular responses to IFN-c are mediated by its …

Cellular senescence is a stress response that activates innate immune cells, but little is
known about its interplay with the adaptive immune system. Here, we show that senescent …

Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor
immunity. To delineate the DC states associated with productive anti-tumor T cell immunity …

Abstract Up to 2.8× 10 7 fibroblast-like cells displaying an abundant presence of
mesenchymal stem cell (MSC) markers CD73, CD90, CD105 and a low level of HLA-I …

Intrauterine viral infections during pregnancy by pathogens such as Zika virus,
Cytomegalovirus, Rubella and Herpes Simplex virus can lead to prenatal as well as …

IM-ADRs remain a challenge in persons living with HIV. The complexities posed by
polypharmacy, overlapping drug toxicities, drug interactions, overlap of IM-ADRs with other …

Mucosa-associated invariant T (MAIT) cells are unconventional, innate-like T lymphocytes
that recognize vitamin B metabolites of microbial origin among other antigens displayed by …

Human leukocyte antigen (HLA)-F adjacent transcript 10 (FAT10) also called ubiquitin D
(UBD) is a member of the ubiquitin-like modifier (ULM) family. The FAT10 gene is localized …

Introduction Since its discovery, the hemochromatosis protein HFE has been primarily
defined by its role in iron metabolism and homeostasis, and its involvement in the genetic …