Discovering multifaceted role of vanillic acid beyond flavours: Nutraceutical and therapeutic potential

J Kaur, M Gulati, SK Singh, G Kuppusamy… - Trends in Food Science …, 2022 - Elsevier
Background Vanillic acid is a phenolic compound, found in various dietary sources and
medicinal plants. Apart from its extraction from these biological sources, it is also …

Natural sources, pharmacokinetics, biological activities and health benefits of hydroxycinnamic acids and their metabolites

M Sova, L Saso - Nutrients, 2020 - mdpi.com
Hydroxycinnamic acids (HCAs) are important natural phenolic compounds present in high
concentrations in fruits, vegetables, cereals, coffee, tea and wine. Many health beneficial …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Beneficial effects of dietary polyphenols on high-fat diet-induced obesity linking with modulation of gut microbiota

J Liu, Z He, N Ma, ZY Chen - Journal of Agricultural and Food …, 2019 - ACS Publications
Obesity is caused by an imbalance of energy intake and expenditure. It is characterized by a
higher accumulation of body fat with a chronic low-grade inflammation. Many reports have …

Flavored e-cigarette liquids and cinnamaldehyde impair respiratory innate immune cell function

PW Clapp, EA Pawlak, JT Lackey… - … of Physiology-Lung …, 2017 - journals.physiology.org
Innate immune cells of the respiratory tract are the first line of defense against pathogenic
and environmental insults. Failure of these cells to perform their immune functions leaves …

Protective effect of vanillic acid against diabetes and diabetic nephropathy by attenuating oxidative stress and upregulation of NF‐κB, TNF‐α and COX‐2 proteins in …

B Singh, A Kumar, H Singh, S Kaur… - Phytotherapy …, 2022 - Wiley Online Library
Diabetes is the most prevalent disorder in the world characterized by uncontrolled high
blood glucose levels and nephropathy is one of the chief complications allied with …

Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice

FU Amin, SA Shah, MO Kim - Scientific reports, 2017 - nature.com
Increasing evidence demonstrates that β-amyloid (Aβ) elicits oxidative stress, which
contributes to the pathogenesis and disease progression of Alzheimer's disease (AD). The …

Bioactive compounds (BACs): A novel approach to treat and prevent cardiovascular diseases

SRU Din, S Saeed, SU Khan, FA Kiani… - Current Problems in …, 2023 - Elsevier
Cardiovascular diseases (CVDs) are one of the leading disorders of serious death and
cause huge economic loss to patients and society. It is estimated that about 18 million …

[HTML][HTML] Higher dietary anthocyanin and flavonol intakes are associated with anti-inflammatory effects in a population of US adults

A Cassidy, G Rogers, JJ Peterson, JT Dwyer… - The American journal of …, 2015 - Elsevier
Background: Although growing evidence from trials and population-based studies has
supported a protective role for flavonoids in relation to risk of certain chronic diseases, the …

Vanillic acid inhibits inflammatory pain by inhibiting neutrophil recruitment, oxidative stress, cytokine production, and NFκB activation in mice

C Calixto-Campos, TT Carvalho… - Journal of natural …, 2015 - ACS Publications
Vanillic acid (1) is a flavoring agent found in edible plants and fruits. It is an oxidized form of
vanillin. Phenolic compounds form a substantial part of plant foods used as antioxidants with …