Heart failure with preserved ejection fraction: a review

MM Redfield, BA Borlaug - Jama, 2023 - jamanetwork.com
Importance Heart failure with preserved ejection fraction (HFpEF), defined as HF with an EF
of 50% or higher at diagnosis, affects approximately 3 million people in the US and up to 32 …

Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

[HTML][HTML] Semaglutide in patients with heart failure with preserved ejection fraction and obesity

MN Kosiborod, SZ Abildstrøm, BA Borlaug… - … England Journal of …, 2023 - Mass Medical Soc
Background Heart failure with preserved ejection fraction is increasing in prevalence and is
associated with a high symptom burden and functional impairment, especially in persons …

Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular …

OA Smiseth, DA Morris, N Cardim… - European Heart …, 2022 - academic.oup.com
Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection
fraction (EF) and the condition is termed heart failure with preserved ejection fraction …

How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association …

B Pieske, C Tschöpe, RA De Boer… - European heart …, 2019 - academic.oup.com
Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF)
remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA–PEFF …

Evaluation and management of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2020 - nature.com
Heart failure with preserved ejection fraction (HFpEF) has grown to become the dominant
form of heart failure worldwide, in tandem with ageing of the general population and the …

Atrial dysfunction in patients with heart failure with preserved ejection fraction and atrial fibrillation

YNV Reddy, M Obokata, FH Verbrugge, G Lin… - Journal of the American …, 2020 - jacc.org
Background Paroxysmal and permanent atrial fibrillation (AF) are common in heart failure
with preserved ejection fraction (HFpEF). Objectives This study sought to determine the …

A simple, evidence-based approach to help guide diagnosis of heart failure with preserved ejection fraction

YNV Reddy, RE Carter, M Obokata, MM Redfield… - Circulation, 2018 - Am Heart Assoc
Background: Diagnosis of heart failure with preserved ejection fraction (HFpEF) is
challenging in euvolemic patients with dyspnea, and no evidence-based criteria are …

Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality

FH Verbrugge, K Omote, YNV Reddy… - European heart …, 2022 - academic.oup.com
Background A substantial proportion of patients with heart failure (HF) with preserved
ejection fraction (HFpEF) present with normal natriuretic peptide (NP) levels. The …

Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial

GA Lewis, S Dodd, D Clayton, E Bedson, H Eccleson… - Nature Medicine, 2021 - nature.com
In heart failure with preserved ejection fraction (HFpEF), the occurrence of myocardial
fibrosis is associated with adverse outcome. Whether pirfenidone, an oral antifibrotic agent …