Chirality is one of the most important structural features in biological systems. Peptides, as a
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …

Alzheimer's disease (AD) will affect around 115 million people worldwide by the year 2050.
It is associated with the accumulation of misfolded and aggregated proteins (β-amyloid and …

Periodontitis is a localized infectious disease caused by periodontopathic bacteria, such as
Porphyromonas gingivalis. Recently, it has been suggested that bacterial infections may …

Amyloidogenesis has been implicated in a broad spectrum of diseases in which amyloid
protein is invariably misfolded and deposited in cells and organs. Alzheimer's disease is one …

Highlights•We review recent drugs mainly targeting Aβ and how they were identified.•We
report their results from in vitro and in vivo experiments and clinical trials.•We describe …

The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …

Alzheimer's disease (AD) is a progressive neurodegenerative disease with no clinically
accepted treatment to cure or halt its progression. The worldwide effort to develop peptide …

The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system
(CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the …

Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …

Protein misfolding into amyloid fibrils is linked to more than 40 as yet incurable cell‐and
neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and type 2 …