The pathogenesis of gastroesophageal reflux disease (GERD) is complex and involves
changes in reflux exposure, epithelial resistance, and visceral sensitivity. The gastric …

Up to 40% of patients with symptoms suspicious of gastroesophageal reflux disease (GERD)
do not respond completely to proton pump inhibitor (PPI) therapy. The term “refractory …

Importance Long-term results from randomized clinical trials comparing laparoscopic sleeve
gastrectomy (LSG) with laparoscopic Roux-en-Y-gastric bypass (LRYGB) are limited …

A surgical instrument includes an end effector having a clevis and first and second jaws
mutually rotatable between open and closed positions. The jaws are proximally directed and …

An apparatus includes an elongated member configured for transoral placement into a
stomach, and a distal end effector including first and second members configured to engage …

An apparatus includes an elongated member configured for transoral placement into a
stomach, and a distal end effector including first and second members configured to engage …

A surgical instrument includes an end effector having a clevis and first and second jaws
mutually rotatable between open and closed positions. The jaws are proximally directed and …

Background Gastroesophageal reflux disease (GERD) is one of the most frequent benign
disorders of the upper gastrointestinal tract. Management of GERD has always been …

Hiatus hernia refers to conditions in which elements of the abdominal cavity, most commonly
the stomach, herniate through the oesophageal hiatus into the mediastinum. With the most …

Background & Aims Transoral esophagogastric fundoplication (TF) can decrease or
eliminate features of gastroesophageal reflux disease (GERD) in some patients whose …