In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation …

Introduction: Cystic fibrosis (CF) is a life-shortening condition with no cure. Available
therapies relieving the symptoms of CF are complex and time-consuming. A comprehensive …

BACKGROUND Poor treatment adherence is common in cystic fibrosis (CF) and may lead to
worse health outcomes and greater health-care use. This study evaluated associations of …

Background Patients with cystic fibrosis (CF) have increasing treatment complexity and high
treatment burden. We describe trends in treatment complexity and evaluate its relationship …

Inhaled antibiotics dramatically improve targeting of drug to the site of respiratory infections,
while simultaneously minimizing systemic exposure and associated toxicity. The high local …

Much of the improvement in the survival of individuals with cystic fibrosis (CF) is due to
advancements in antimicrobial treatments. New aerosolized antibiotic formulations have …

Background Adherence to treatment is often reported to be low in children with cystic
fibrosis. Adherence in cystic fibrosis is an important research area and more research is …

Objective: Depression is a known barrier to regimen adherence for chronic conditions.
Despite elevated depression rates and complex regimens for people with cystic fibrosis …

Tigecycline (TIG) is a broad-spectrum antibiotic that has been approved for the treatment of
a number of complicated infections, including community-acquired bacterial pneumonia …

Background We aimed to determine adherence to inhaled antibiotics, other respiratory
medicines and airway clearance and to determine the association between adherence to …