Discovery of Natural Bisbenzylisoquinoline Analogs from the Library of Thai Traditional Plants as SARS-CoV-2 3CLPro Inhibitors: In Silico Molecular Docking, Molecular …

N Khamto, K Utama, S Tateing… - Journal of Chemical …, 2023 - ACS Publications
The emergence of SARS-CoV-2 in December 2019 has become a global issue due to the
continuous upsurge in patients and the lack of drug efficacy for treatment. SARS-CoV-2 …

Overview of the SARS-CoV-2 nucleocapsid protein

A Eltayeb, F Al-Sarraj, M Alharbi, R Albiheyri… - International Journal of …, 2024 - Elsevier
Since the emergence of SARS-CoV in 2003, researchers worldwide have been toiling away
at deciphering this virus's biological intricacies. In line with other known coronaviruses, the …

In Silico Studies on Psilocybin Drug Derivatives Against SARS-CoV-2 and Cytokine Storm of Human Interleukin-6 Receptor

FI Khan, F Hassan, D Lai - Frontiers in Immunology, 2022 - frontiersin.org
Various metabolites identified with therapeutic mushrooms have been found from different
sources and are known to have antibacterial, antiviral, and anticancer properties. Over …

Phytovid19: a compilation of phytochemicals research in coronavirus

A Bhargav, P Chaurasia, R Kumar… - Structural Chemistry, 2022 - Springer
The COVID-19 pandemic has immensely impacted global health causing colossal damage.
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has …

In Silico and In Vivo Evaluation of the Maqui Berry (Aristotelia chilensis (Mol.) Stuntz) on Biochemical Parameters and Oxidative Stress Markers in a Metabolic …

EL Castillo-García, AL Cossio-Ramírez… - Metabolites, 2023 - mdpi.com
Metabolic syndrome (MetS) is a complex disease that includes metabolic and physiological
alterations in various organs such as the heart, pancreas, liver, and brain. Reports indicate …

Computational exploration of the dual role of the phytochemical fortunellin: antiviral activities against SARS-CoV-2 and immunomodulatory abilities against the host

S Agrawal, E Pathak, R Mishra, V Mishra… - Computers in biology …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections generate
approximately one million virions per day, and the majority of available antivirals are …

The molecular basis of the effect of temperature on the structure and function of SARS-CoV-2 spike protein

FI Khan, KA Lobb, D Lai - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
The remarkable rise of the current COVID-19 pandemic to every part of the globe has raised
key concerns for the current public healthcare system. The spike (S) protein of SARS-CoV-2 …

Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganisms

F Almasi, W Dang, F Mohammadipanah… - Archives of Pharmacal …, 2022 - Springer
In addition to the typical respiratory manifestations, various disorders including involvement
of the nerve system have been detected in COVID-19 ranging from 22 to 36%. Although …

Fangchinoline Exerts Anticancer Effects on Colorectal Cancer Cells by Evoking Cell Apoptosis via Endoplasmic Reticulum Stress

X Jiang, Y Hu, J Peng, X Luo, L Su, Y Tang - Bulletin of Experimental …, 2023 - Springer
We studied the anti-tumor effect of fangchinoline (FAN) against human colorectal cancer cell
lines CCL-244 and SW480 and analyzed the mechanism of FAN action. The cell viability …

Herbal Medicines for COVID-19: The Impact of Alkaloids on Protein Targets

B Yingngam - Traditional and Herbal Medicines for COVID-19 - taylorfrancis.com
COVID-19, caused by the SARS-CoV-2 virus, has posed significant global health
challenges. Despite the development of vaccines and antiviral drugs, the search for effective …