Off-target pharmacological activity at various kinases: Potential functional and pathological side effects
JR Green, PKS Mahalingaiah… - … of Pharmacological and …, 2023 - Elsevier
In drug discovery, during the lead optimization and candidate characterization stages, novel
small molecules are frequently evaluated in a battery of in vitro pharmacology assays to …
small molecules are frequently evaluated in a battery of in vitro pharmacology assays to …
High throughput screen in a co-culture model to uncover therapeutic strategies to potentiate the cancer-inhibiting properties of the tumor-stroma in pancreatic cancer
J Mason, J Cumming, AU Eriksson, C Binder… - bioRxiv, 2022 - biorxiv.org
P ancreatic stellate c ells (PSCs) differentiate into multiple subtypes of c ancer a ssociated
fibroblasts (CAFs) that modulate disease progression in p ancreatic d uctal a deno c …
fibroblasts (CAFs) that modulate disease progression in p ancreatic d uctal a deno c …
The identification and functional evaluation of novel cancer-associated fibroblast subtypes and matrisome proteins in pancreatic cancer
J Cumming - 2023 - diva-portal.org
Over the course of reading this introduction I hope to convey to you the reasons behind the
work that was conducted during the course of my PhD. This work has been centred around …
work that was conducted during the course of my PhD. This work has been centred around …