Microfluidic point-of-care (POC) devices in early diagnosis: A review of opportunities and challenges

SM Yang, S Lv, W Zhang, Y Cui - Sensors, 2022 - mdpi.com
The early diagnosis of infectious diseases is critical because it can greatly increase recovery
rates and prevent the spread of diseases such as COVID-19; however, in many areas with …

Present status of microfluidic PCR chip in nucleic acid detection and future perspective

S Chen, Y Sun, F Fan, S Chen, Y Zhang… - TrAC Trends in …, 2022 - Elsevier
Polymerase chain reaction (PCR) amplifies specific fragment of DNA molecules and has
been extensively applied in fields of pathogens and gene mutation detection, food safety …

Recent advances in microfluidic devices for foodborne pathogens detection

D Gao, Z Ma, Y Jiang - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Rapid and accurate detection of foodborne pathogens is a powerful and effective strategy to
prevent the outbreak of foodborne diseases. Conventional detection methods like the plate …

Microfluidic paper-based chips in rapid detection: Current status, challenges, and perspectives

X Qin, J Liu, Z Zhang, J Li, L Yuan, Z Zhang… - TrAC Trends in Analytical …, 2021 - Elsevier
Microfluidic paper-based chips (μPCs) are micro-laboratory analysis systems that use paper
instead of traditional microfluidic substrate materials and miniaturize biochemical reactions …

Applications of fiber-optic biochemical sensor in microfluidic chips: A review

Y Zhao, X Hu, S Hu, Y Peng - Biosensors and Bioelectronics, 2020 - Elsevier
An overview of applications of fiber-optic biochemical sensor in microfluidic chips was
carried out with a specific focus on different fiber-optic sensors used on chip, detection …

based point-of-care immunoassays: Recent advances and emerging trends

F Li, M You, S Li, J Hu, C Liu, Y Gong, H Yang… - Biotechnology …, 2020 - Elsevier
Immunoassay has been routinely used in hospitals and central labs. Nowadays, to further
meet the requirement of widespread applications of immunoassays, it is urgently needed to …

Microfluidic single-cell manipulation and analysis: Methods and applications

T Luo, L Fan, R Zhu, D Sun - Micromachines, 2019 - mdpi.com
In a forest of a hundred thousand trees, no two leaves are alike. Similarly, no two cells in a
genetically identical group are the same. This heterogeneity at the single-cell level has been …

Machining water through laser cutting of nanoparticle-encased water pancakes

J Niu, W Liu, JX Li, X Pang, Y Liu, C Zhang… - Nature …, 2023 - nature.com
Due to the inherent disorder and fluidity of water, precise machining of water through laser
cutting are challenging. Herein we report a strategy that realizes the laser cutting machining …

Recent progress of microfluidic chips in immunoassay

K Wu, X He, J Wang, T Pan, R He, F Kong… - … in Bioengineering and …, 2022 - frontiersin.org
Microfluidic chip technology is a technology platform that integrates basic operation units
such as processing, separation, reaction and detection into microchannel chip to realize low …

Recent advances in biological sample preparation methods coupled with chromatography, spectrometry and electrochemistry analysis techniques

Z Niu, W Zhang, C Yu, J Zhang, Y Wen - TrAC Trends in Analytical …, 2018 - Elsevier
Biological samples are complex and often contain many proteins, lipids and other
contaminants, which affect the separation and ionization properties of the analytes …