Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways

X Yong, B Tang, BS Li, R Xie, CJ Hu, G Luo… - Cell communication and …, 2015 - Springer
Helicobacter pylori (H. pylori) infection is strongly associated with the development of gastric
diseases but also with several extragastric diseases. The clinical outcomes caused by H …

The epidemiology of Helicobacter pylori infection in Europe and the impact of lifestyle on its natural evolution toward stomach cancer after infection: A systematic …

K Venneman, I Huybrechts, MJ Gunter… - …, 2018 - Wiley Online Library
Background Helicobacter pylori is a recognized cause of stomach cancer, but only a fraction
of infected subjects develop cancer. This systematic review 1, summarizes the prevalence of …

How dietary factors affect DNA methylation: lesson from epidemiological studies

A Maugeri, M Barchitta - Medicina, 2020 - mdpi.com
Over the past decades, DNA methylation has been proposed as a molecular mechanism
underlying the positive or negative effects of diet on human health. Despite the number of …

Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway

X Zhang, Y Zhu, W Duan… - Molecular medicine …, 2015 - spandidos-publications.com
Gastric cancer is one of the most common forms of malignant tumor, and the development of
anti‑gastric cancer drugs with minimal toxicity is of clinical importance. Allicin is extracted …

[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity

P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …

Risk factors for gastric precancerous and cancers lesions in Latin American counties with difference gastric cancer risk

L Flores-Luna, MM Bravo, E Kasamatsu, ECL Ponce… - Cancer …, 2020 - Elsevier
Objective To evaluate the risk factors associated with pre-neoplastic lesions and gastric
cancer in countries with different cancer risk in Latin America. Methods 1222 questionnaires …

[HTML][HTML] Pathogenic mechanisms of the oncoprotein CagA in H. pylori-induced gastric cancer

SY Chen, RG Zhang, GC Duan - Oncology reports, 2016 - spandidos-publications.com
Infection with Helicobacter pylori is the strongest risk factor for the development of chronic
gastritis, gastric ulcer and gastric carcinoma. The majority of the H. pylori-infected population …

Multiplex H. pylori Serology and Risk of Gastric Cardia and Noncardia Adenocarcinomas

R Shakeri, R Malekzadeh, D Nasrollahzadeh… - Cancer research, 2015 - AACR
The reported associations with gastric adenocarcinoma and seropositivity to different
Helicobacter pylori antigens using multiplex serology have not been consistent across …

Helicobacter pylori: Genomic Insight into the Host‐Pathogen Interaction

KP Haley, JA Gaddy - International journal of genomics, 2015 - Wiley Online Library
The advent of genomic analyses has revolutionized the study of human health. Infectious
disease research in particular has experienced an explosion of bacterial genomic …

DNA methylation, colon cancer and Mediterranean diet: results from the EPIC-Italy cohort

F Fasanelli, MT Giraudo, P Vineis, V Fiano, G Fiorito… - Epigenetics, 2019 - Taylor & Francis
The biological mechanisms through which adherence to Mediterranean Diet (MD) protects
against colon cancer (CC) are poorly understood. Evidence suggests that chronic …