The rapid construction of three dimensional spiro-and fused cyclic skeletons is a challenging
goal in synthetic organic chemistry. In this context, readily accessible 2-arylidene-1, 3 …

Diarylethenes (DAEs) are an established class of photochromic molecules, but their effective
incorporation into pre-existing targets is synthetically difficult. Here we describe a new class …

Reactions of 3-benzylidene succinimides with 2-substituted 2-hydroxy-indane-1, 3-diones
and unsaturated pyrazolones are carried out under basic conditions to afford spirocyclized …

An efficient, high yielding method has been developed for the synthesis of diversity
tetrahydro-4H-indol-4-one derivatives via a three component, one pot domino reaction from …

A set of di-and tetra-copper (I) compounds [Cu2 (L1H) 2][BArF] 2 (1)(L1H= bis (5, 7-dimethyl-
1, 8-naphthyridin-2-yl) amine; BArF=[B {C6H3 (CF3) 2} 4]) and [Cu4 (L1) 2 (L2) 2][BNBF] 2 …

Abstract Synthesis of functionalized 1, 3‐indandiones containing‐cyclopentenones and‐
benzotropones has been achieved by the reaction of 1, 5‐diphenylpenta‐1, 4‐diyn‐3‐ones …

A metal-free domino [3+ 2] cycloaddition is reported to construct naphtho [2, 3-d][1, 2, 3]
triazole-4, 9-dione derivatives and provide an alternative approach to the azide–alkyne …

There is an urgent need to propose effective treatments for Alzheimer's disease (AD).
Although the origin of the disease is poorly understood, several therapeutic options have …

A novel, metal-free, base promoted sp2 C–H functionalization in the sulfonamidation of 1, 4-
naphthoquinones via a [3+ 2] cycloaddition reaction using sulfonyl azides under mild …

La fibrillation anormale de la protéine tau est un phénomène présent dans de nombreuses
maladies neurodégénératives, dont la maladie d'Alzheimer, et conduit à la formation de …