Rational design of dna hydrogels based on molecular dynamics of polymers

Y Li, R Chen, B Zhou, Y Dong, D Liu - Advanced Materials, 2024 - Wiley Online Library
In recent years, DNA has emerged as a fascinating building material to engineer hydrogel
due to its excellent programmability, which has gained considerable attention in biomedical …

Injectable hydrogels as promising in situ therapeutic platform for cartilage tissue engineering

R Cai, Y Shan, F Du, Z Miao, L Zhu, L Hang… - International Journal of …, 2024 - Elsevier
Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …

Constructing stiffness tunable DNA hydrogels based on DNA modules with adjustable rigidity

Z Shi, Y Li, X Du, D Liu, Y Dong - Nano Letters, 2024 - ACS Publications
DNA hydrogel represents a potent material for crafting biological scaffolds, but the toolbox to
systematically regulate the mechanical property is still limited. Herein, we have provided a …

Engineering the physical microenvironment into neural organoids for neurogenesis and neurodevelopment

M Li, H Sun, Z Hou, S Hao, L Jin, B Wang - Small, 2024 - Wiley Online Library
Understanding the signals from the physical microenvironment is critical for deciphering the
processes of neurogenesis and neurodevelopment. The discovery of how surrounding …

Programmable Artificial Skins Accomplish Antiscar Healing with Multiple Appendage Regeneration

M Xiong, X Yang, Z Shi, J Xiang, H Gao, S Ji… - Advanced …, 2024 - Wiley Online Library
Functional appendage regeneration is essential for skin rehabilitation, but it has always
failed by current existing healing approaches, owing to their inefficacy in preventing …

A DNA/Poly‐(L‐lysine) Hydrogel with Long Shelf‐Time for 3D Cell Culture

J Tang, J Wang, J Ou, Z Cui, C Yao, D Yang - Small Methods, 2024 - Wiley Online Library
Deoxyribonucleic acid (DNA)‐based hydrogels are emerging as promising functional
materials for biomedical applications. However, the shelf‐time of DNA hydrogels in …

DNA Cryogels with Anisotropic Mechanical and Responsive Properties for Specific Cell Capture and Release

Y Mu, X Wang, X Du, PP He, W Guo - Journal of the American …, 2024 - ACS Publications
Due to their programmable stimuli-responsiveness, excellent biocompatibility, and water-
rich and soft structures similar to biological tissues, smart DNA hydrogels hold great promise …

Physical cues of scaffolds promote peripheral nerve regeneration

W Cao, Y Zhang, L Li, B Liu, J Ding… - Applied Physics Reviews, 2024 - pubs.aip.org
The effective treatment of long-gap peripheral nerve injury (PNI) remains a challenge in
clinical settings. The autograft, the gold standard for the long-gap PNI therapy, has several …

Application of smart-responsive hydrogels in nucleic acid and nucleic acid-based target sensing: A review

M Song, J Zhang, K Shen, Y Hu, W Shen… - Biosensors and …, 2024 - Elsevier
In recent years, nucleic acid-related sensing and detection have become essential in clinical
diagnostics, treatment and genotyping, especially in connection with the Human Genome …

Advanced Smart Biomaterials for Regenerative Medicine and Drug Delivery Based on Phosphoramidite Chemistry: From Oligonucleotides to Precision Polymers

B Yang, T Cui, L Guo, L Dong, J Wu, Y Xing… - …, 2024 - ACS Publications
Over decades of development, while phosphoramidite chemistry has been known as the
leading method in commercial synthesis of oligonucleotides, it has also revolutionized the …