Pathogenesis and virulence of herpes simplex virus

S Zhu, A Viejo-Borbolla - Virulence, 2021 - Taylor & Francis
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

[HTML][HTML] Redefining chronic viral infection

HW Virgin, EJ Wherry, R Ahmed - Cell, 2009 - cell.com
Viruses that cause chronic infection constitute a stable but little-recognized part of our
metagenome: our virome. Ongoing immune responses hold these chronic viruses at bay …

Herpes simplex virus infections

RJ Whitley, B Roizman - The lancet, 2001 - thelancet.com
Herpes simplex virus (HSV) is a member of the herpesviridae family. Recognised since
ancient Greek times, the virus frequently infects human beings, causing a range of diseases …

Efficacy results of a trial of a herpes simplex vaccine

RB Belshe, PA Leone, DI Bernstein… - … England Journal of …, 2012 - Mass Medical Soc
Background Two previous studies of a herpes simplex virus type 2 (HSV-2) subunit vaccine
containing glycoprotein D in HSV-discordant couples revealed 73% and 74% efficacy …

Male infertility: a public health issue caused by sexually transmitted pathogens

F Gimenes, RP Souza, JC Bento, JJV Teixeira… - Nature Reviews …, 2014 - nature.com
Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria,
viruses and protozoa, and can induce male infertility through multiple pathophysiological …

Viral threat to male fertility

W Liu, R Han, H Wu, D Han - Andrologia, 2018 - Wiley Online Library
The detrimental effects of Zika virus (ZIKV) infection on mouse testicular functions have
reminded a viral threat to male fertility. A broad range of virus families has tropism for male …

Genital herpes

R Gupta, T Warren, A Wald - The Lancet, 2007 - thelancet.com
Genital herpes is the main cause of genital ulcers worldwide; the prevalence of herpes
simplex virus (HSV) type 2 infections in the general population ranges from 10% to 60 …

Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management

M Fatahzadeh, RA Schwartz - Journal of the American Academy of …, 2007 - Elsevier
Eight of the more than 80 known herpesviruses are human pathogens. Human herpes
simplex virus (HSV) is a contagious infection with a large reservoir in the general population …

Herpes simplex virus epidemiology and ocular importance

TJ Liesegang - Cornea, 2001 - journals.lww.com
Purpose. To review the changing epidemiology of herpes simplex disease and correlate it
with the epidemiology of ocular herpes simplex disease. Method. A review of pertinent …

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

J Zhu, T Peng, C Johnston, K Phasouk, AS Kask… - Nature, 2013 - nature.com
Most herpes simplex virus 2 (HSV-2) reactivations in humans are subclinical and associated
with rapid expansion and containment of virus. Previous studies have shown that CD8+ T …