Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

S Deleu, K Machiels, J Raes, K Verbeke, S Vermeire - EBioMedicine, 2021 - thelancet.com
The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …

Gut microbiota-derived metabolites as central regulators in metabolic disorders

A Agus, K Clément, H Sokol - Gut, 2021 - gut.bmj.com
Metabolic disorders represent a growing worldwide health challenge due to their
dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact …

SCFA: mechanisms and functional importance in the gut

C Martin-Gallausiaux, L Marinelli… - Proceedings of the …, 2021 - cambridge.org
In recent years, the importance of the gut microbiota in human health has been revealed and
many publications have highlighted its role as a key component of human physiology …

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

ME Sanders, DJ Merenstein, G Reid… - Nature reviews …, 2019 - nature.com
Probiotics and prebiotics are microbiota-management tools for improving host health. They
target gastrointestinal effects via the gut, although direct application to other sites such as …

Introduction to the human gut microbiota

E Thursby, N Juge - Biochemical journal, 2017 - portlandpress.com
The human gastrointestinal (GI) tract harbours a complex and dynamic population of
microorganisms, the gut microbiota, which exert a marked influence on the host during …

Dietary fiber‐derived short‐chain fatty acids: A potential therapeutic target to alleviate obesity‐related nonalcoholic fatty liver disease

S Zhang, J Zhao, F Xie, H He, LJ Johnston… - Obesity …, 2021 - Wiley Online Library
Over the past several decades, increasing global prevalence of obesity‐related
nonalcoholic fatty liver disease (NAFLD) has been one of main challenges to human health …

[HTML][HTML] Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics

TJ Ashaolu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Comprehensive studies conducted on the link between the gut microbiome and immunity in
recent decades have correspondingly led to ever increasing interests in functional foods …

Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

Impact of gut microbiota and microbiota-related metabolites on hyperlipidemia

X Jia, W Xu, L Zhang, X Li, R Wang… - Frontiers in Cellular and …, 2021 - frontiersin.org
Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

Association of metabolic dysfunction-associated fatty liver disease with kidney disease

TY Wang, RF Wang, ZY Bu, G Targher… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of fat in more
than 5% of hepatocytes in the absence of excessive alcohol consumption and other …