Integrins are vital surface adhesion receptors that mediate interactions between the
extracellular matrix (ECM) and cells and are essential for cell migration and the …

Integrins mediate adhesive interactions between cells and their environment, including
neighboring cells and extracellular matrix (ECM). These heterodimeric transmembrane …

Integrins are transmembrane receptors that possess distinct ligand-binding specificities in
the extracellular domain and signaling properties in the cytoplasmic domain. While most …

Prostate cancer remains a life-threatening disease among men worldwide. The majority of
PCa-related mortality results from metastatic disease that is characterized by metastasis of …

Liquid biopsy has been rapidly developed in recent years due to its advantages of non-
invasiveness and real-time sampling in cancer prognosis and diagnosis. Exosomes are …

Prostate cancer (PCa) is the second most common cause of cancer-related mortality among
men in the developed world. Conventional anti-PCa therapies are not effective for patients …

Extracellular vesicles (EVs) have attracted interest due to their ability to provide diagnostic
information from liquid biopsies. Cells constantly release vesicles divers in size, content and …

Integrins are main cell adhesion receptors serving as linker attaching cells to extracellular
matrix (ECM) and bidirectional hubs transmitting biochemical and mechanical signals …

The development of new antitumor drugs depends mainly upon targeting tumor cells
precisely. Trophoblast surface antigen 2 (Trop-2) is a type I transmembrane glycoprotein …

Prostate cancer (PCa) is the most common solid tumor in men. While patients with local PCa
have better prognostic survival, patients with metastatic PCa have relatively high mortality …