Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease
(COPD) and affects both ventilatory and nonventilatory muscle groups. It represents a very …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Background There is considerable heterogeneity in the rate of lung function decline in
chronic obstructive pulmonary disease (COPD), the determinants of which are largely …

COPD and obstructive sleep apnoea (OSA) are highly prevalent and different clinical COPD
phenotypes that influence the likelihood of comorbid OSA. The increased lung volumes and …

The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter,
longitudinal analysis of> 10,000 subjects, including smokers with a≥ 10 pack-year history …

In 2014, the European Respiratory Society published a statement on nutritional assessment
and therapy in COPD. Since then, increasing research has been performed on the role of …

Dysregulated lipid metabolism plays crucial roles in various diseases, including diabetes
mellitus, cancer, and neurodegeneration. Recent studies suggest that alterations in major …

Rationale: Patients with chronic obstructive pulmonary disease (COPD) and type 2 diabetes
(T2D) have worse clinical outcomes compared with patients without metabolic …

Nutritional abnormalities are frequent in different chronic respiratory diseases such as
chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF) …

Obesity is mostly associated with adverse health consequences, but may also elicit
favorable effects under chronic conditions. This “obesity paradox” is under debate for …