Initially identified as an actin-binding protein containing a PSD95-DLG-ZO1 Domain (PZD
domain), Synaptopodin 2 (SYNPO2) has long been considered a structural protein …

Highlights•Cell adhesion to the extracellular matrix (ECM) is vital for multicellular
life.•Complexes of structural and signalling proteins link the ECM to the cytoskeleton.• …

Ovarian cancer is the leading cause of death from gynecologic cancer worldwide. High-
grade serous carcinoma (HGSC) is the most common and deadliest subtype of ovarian …

The venous system has been historically understudied despite its critical roles in blood
distribution, heart function, and systemic immunity. This study dissects the microanatomy of …

Synaptopodin 2 (SYNPO2) plays a pivotal role in regulating tumor growth, development and
progression in bladder urothelial Carcinoma (BLCA). However, the precise biological …

Gastric cancer peritoneal metastases (GCPM) is a leading cause of GC‐related death. Early
detection of GCPM is critical for improving the prognosis of advanced GC. Differentially …

Introduction Synaptopodin 2 (SYNPO2) is a functioning protein. It has been detected in
many malignancies. But the relation between SYNPO2 and breast cancer (BC) is unclear …

Background Differentiation of mouse trophoblast stem cells (TSCs) to trophoblast giant cells
(TGCs) has been widely used as a model system to study placental development and …

Temperature strongly modulates muscle development and growth in ectothermic teleosts;
however, the underlying mechanisms remain largely unknown. In this study, primary cultures …

Focal adhesions are highly dynamic multi-protein complexes found at the cell surface and
effectively link the cell's internal cytoskeleton to a complex mixture of macromolecules …