The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …

Cytoplasmic stress granules (SGs) are generally triggered by stress-induced translation
arrest for storing mRNAs. Recently, it has been shown that SGs exert anti-viral functions due …

A key to tackling the coronavirus disease 2019 (COVID-19) pandemic is to understand how
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) manages to outsmart host …

Cells have evolved highly specialized sentinels that detect viral infection and elicit an
antiviral response. Among these, the stress-sensing protein kinase R, which is activated by …

Background eIF2α is a regulatory node that controls protein synthesis initiation by its
phosphorylation or dephosphorylation. General control nonderepressible-2 (GCN2), protein …

Antiviral responses of interferons (IFNs) are crucial in the host immune response, playing a
relevant role in controlling viralw infections. Three types of IFNs, type I (IFN-α, IFN-β), II (IFN …

Ras-GTPase-activating protein (SH3 domain)-binding protein (G3BP) is an RNA binding
protein. G3BP is a key component of stress granules (SGs) and can interact with many host …

Summary G3BP1/2 are paralogous proteins that promote stress granule formation in
response to cellular stresses, including viral infection. The nucleocapsid (N) protein of …

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals,
which has been regarded as a persistent challenge for the livestock industry in many …