Targeting FMN, TPP, SAM-I, and glmS Riboswitches with Chimeric Antisense Oligonucleotides for Completely Rational Antibacterial Drug Development

N Pavlova, M Traykovska, R Penchovsky - Antibiotics, 2023 - mdpi.com
Antimicrobial drug resistance has emerged as a significant challenge in contemporary
medicine due to the proliferation of numerous bacterial strains resistant to all existing …

Revealing the degrading-possibility of methyl red by two azoreductases of Anoxybacillus sp. PDR2 based on molecular docking

S Zhang, L Feng, Y Han, Z Xu, L Xu, X An, Q Zhang - Chemosphere, 2024 - Elsevier
Azo dyes, as the most widely used synthetic dyes, are considered to be one of the culprits of
water resources and environmental pollution. Anoxybacillus sp. PDR2 is a thermophilic …

Development of a framework to characterise and evolve riboswitches

MXL Jessen - 2023 - eprints.qut.edu.au
Quantifying small molecules inside a cell is a major challenge in biology. Riboswitch-based
biosensors promise to solve this by converting small molecule concentrations into directly …

Mutation-Induced Conformational Changes and Energetics for Binding of FMN Ligand in Flavin Mononucleotide Riboswitch by Molecular Dynamics Simulations

PD Wakchaure, B Ganguly - Croatica Chemica Acta, 2019 - hrcak.srce.hr
Sažetak Riboswitches are the type of regulatory elements present in the untranslated region
of mRNA and specifically bind to the natural ligand to regulate gene expression. This …