Chronic pain is maintained in part by central sensitization, a phenomenon of synaptic
plasticity, and increased neuronal responsiveness in central pain pathways after painful …

2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

Oxaliplatin (OXA) is a commonly used platinum-based chemotherapy drug for colorectal
cancer. OXA-induced peripheral neurotoxcity (OIPN) is a comprehensive adverse reaction of …

Chronic pain is a major public health issue with an incidence of 20–25% worldwide that can
take different forms like neuropathic, cancer-related or inflammatory pain. Chronic pain often …

Accumulating evidence suggests that epigenetic mechanisms may hold great potential in
the field of pain. We systematically reviewed the literature exploring epigenetic mechanisms …

Migraine is a disabling and recurrent neurological disorder characterized by headache
attacks that are often accompanied by sensory and motor disturbances. The value and …

Background The quality of life for millions of people worldwide is affected by chronic pain. In
addition to the effect of chronic pain on well-being, chronic pain has also been associated …

Fibromyalgia and irritable bowel syndrome are common disorders which often coexist in
women with chronic pelvic pain. Like pelvic pain, these disorders describe symptoms …

Vestibulodynia (VBD), an idiopathic pain disorder characterized by erythema and pain of the
vulvar vestibule (the inner aspect of the labia minora and vaginal opening), is the most …

Chronic pain (CP) is an unpleasant sensory and emotional experience associated with, or
resembling that associated with, actual or potential tissue damage lasting longer than 3 …