Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Background Frontotemporal dementia is a highly heritable neurodegenerative disorder. In
about a third of patients, the disease is caused by autosomal dominant genetic mutations …

Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene.
Progranulin consists of seven and a half, tandemly repeated, non-identical copies of the 12 …

Hexanucleotide repeat expansion in C9orf72 represents the most common genetic cause of
familial and sporadic behavioural variant frontotemporal dementia. Previous studies show …

Objective: We aimed to investigate whether cognitive deficits and structural and functional
connectivity changes can be detected before symptom onset in a large cohort of carriers of …

Background: Primary progressive aphasia (PPA) is an untreatable neurodegenerative
disorder that disrupts language functions. Previous studies have demonstrated transcranial …

The presymptomatic stages of frontotemporal dementia (FTD) are still poorly defined and
encompass a long accrual of progressive biological (preclinical) and then clinical …

Frontotemporal dementia (FTD) is a clinically and neuroanatomically heterogeneous
neurodegenerative disorder with multiple underlying genetic and pathological causes …

Functional brain connectivity of the resting-state networks has gained recent attention as a
possible biomarker of Alzheimer's Disease (AD). In this paper, we review the literature of …