Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Heme is a complex of iron and the tetrapyrrole protoporphyrin IX with essential functions in
aerobic organisms. Heme is the prosthetic group of hemoproteins such as hemoglobin and …

Increasing evidence suggests that free haem and iron exert vasculo‐toxic and pro‐
inflammatory effects by activating endothelial and immune cells. In the present retrospective …

It is now understood that hemolysis and the subsequent release of heme into circulation play
a critical role in driving the progression of various diseases. Hemopexin (HPX), a heme …

During red blood cell (RBC) lysis hemoglobin and heme leak out of the cells and cause
damage to the endothelium and nearby tissue. Protective mechanisms exist; however, these …

Heart failure is a leading cause of morbidity and mortality in patients affected by different
disorders associated to intravascular hemolysis. The leading factor is the presence of …

Accumulation of damaged or misfolded proteins resulted from oxidative protein modification
induces endoplasmic reticulum (ER) stress by activating the pathways of unfolded protein …

The multipurpose organelle mitochondria play an essential role (s) in controlling cardiac
muscle contraction. Mitochondria, not only function as the powerhouses and the energy …

Heme, the protoporphyrin IX iron complex is widely present in the human body and it is
involved in oxygen storage, electron transfer, and enzymatic reactions. However, free heme …

Broiler breeder hens allowed ad libitum (Ad) feed intake developed obesity and cardiac
pathogenesis and thereby were susceptible to sudden death. A supplement of 69 µg 25 …