The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …

Objective This study aimed to assess the effects of 9‐hour time‐restricted feeding (TRF),
early (TRFe) or delayed (TRFd), on glucose tolerance in men at risk for type 2 diabetes …

The life of all animals is dominated by alternating feelings of hunger and satiety—the main
involuntary motivations for feeding-related behaviour. Gut bacteria depend fully on their host …

The a 28-amino acid peptide ghrelin was discovered in 1999 as a growth hormone (GH)
releasing peptide. Soon after its discovery, ghrelin was found to increase body weight and …

Background: Men and women differ substantially in regard to degrees of insulin resistance,
body composition, and energy balance. Adipose tissue distribution, in particular the …

Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …

Food intake, energy expenditure and body adiposity are homeostatically regulated. Central
and peripheral signals communicate information about the current state of energy balance to …

Previous studies indicate that leptin secretion is regulated by insulin-mediated glucose
metabolism. Because fructose, unlike glucose, does not stimulate insulin secretion, we …

Studies have found that diabetes and thyroid disorders tend to coexist in patients. Both
conditions involve a dysfunction of the endocrine system. Thyroid disorders can have a …