Role of ROS and RNS sources in physiological and pathological conditions

S Di Meo, TT Reed, P Venditti… - Oxidative medicine and …, 2016 - Wiley Online Library
There is significant evidence that, in living systems, free radicals and other reactive oxygen
and nitrogen species play a double role, because they can cause oxidative damage and …

Redox signaling by reactive electrophiles and oxidants

S Parvez, MJC Long, JR Poganik, Y Aye - Chemical reviews, 2018 - ACS Publications
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Antioxidant enzymes regulation in plants in reference to reactive oxygen species (ROS) and reactive nitrogen species (RNS)

D Kapoor, S Singh, V Kumar, R Romero, R Prasad… - Plant gene, 2019 - Elsevier
Reactive oxygen species (ROS) are generated in the plants during cellular metabolism. But
extreme environmental conditions like drought, salinity or floods etc. lead to an enhanced …

[HTML][HTML] Redox regulation of FoxO transcription factors

LO Klotz, C Sánchez-Ramos, I Prieto-Arroyo… - Redox biology, 2015 - Elsevier
Transcription factors of the forkhead box, class O (FoxO) family are important regulators of
the cellular stress response and promote the cellular antioxidant defense. On one hand …

Obesity induces ovarian inflammation and reduces oocyte quality

AP Snider, JR Wood - Reproduction, 2019 - rep.bioscientifica.com
In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …

[HTML][HTML] Significance of antioxidant potential of plants and its relevance to therapeutic applications

DM Kasote, SS Katyare, MV Hegde… - International journal of …, 2015 - ncbi.nlm.nih.gov
Oxidative stress has been identified as the root cause of the development and progression
of several diseases. Supplementation of exogenous antioxidants or boosting endogenous …

Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum

RJA Wanders, HR Waterham… - Frontiers in cell and …, 2016 - frontiersin.org
Peroxisomes are unique subcellular organelles which play an indispensable role in several
key metabolic pathways which include:(1.) etherphospholipid biosynthesis;(2.) fatty acid …

Reactive oxygen species in normal and tumor stem cells

D Zhou, L Shao, DR Spitz - Advances in cancer research, 2014 - Elsevier
Reactive oxygen species (ROS) play an important role in determining the fate of normal
stem cells. Low levels of ROS are required for stem cells to maintain quiescence and self …

ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER

JL Costello, IG Castro, C Hacker, TA Schrader… - Journal of Cell …, 2017 - rupress.org
Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid
metabolism and form tight structural associations, which were first observed in ultrastructural …

Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes

J Li, L Pan, WG Pembroke, JE Rexach… - Nature …, 2021 - nature.com
Astrocytes play important roles in neurological disorders such as stroke, injury, and
neurodegeneration. Most knowledge on astrocyte biology is based on studies of mouse …