Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

Sexual (and gender)-dimorphism in tolerance to hypobaric hypoxia increasingly matters for
a differential surveillance of human activities at high altitude (HA). At low altitudes, the …

Objectives The effects of altitude residence on ageing, longevity and mortality are poorly
understood. While adaptations to chronic exposure to altitude may exert beneficial effects on …

Background Suicide is a global challenge. Although it is clear that socioeconomic and
demographic factors influence suicide rates, we know little about the impacts of the built …

Objective: Depressive symptoms (depression hereafter) is common in older adults, and
closely associated with environmental factors. This study compared the prevalence of …

Suicide is a serious but preventable public health issue. Several previous studies have
revealed a positive association between altitude and suicide rates at the county level in the …

Over sixteen million people suffer from a depressive episode annually in the United States,
with females affected at twice the rate of males. Little is known about the effects of exposure …

The states of the Mountain West region of the United States consistently have the highest
rates of suicide in the country, a pattern particularly pronounced in older White men …

Suicide is a major public health problem affecting US Veterans and the US in general. Many
variables (eg, demographic, clinical, biological, geographic) have been associated with risk …

The relationship between three markers of chronic hypoxia (altitude, smoking and chronic
obstructive pulmonary disease (COPD)) and suicide risk has not been well-studied. We …