Nanoparticle toxicology
Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …
Cytotoxicity and genotoxicity evaluation of chemically synthesized and functionalized upconversion nanoparticles
AA Ansari, AK Parchur, Y Li, T Jia, R Lv, Y Wang… - Coordination Chemistry …, 2024 - Elsevier
Upconversion nanoparticles (UCNPs) show attractive anti-Stokes characteristics converting
lower-energy photons into higher-energy emissions. The excellent biocompatibility and …
lower-energy photons into higher-energy emissions. The excellent biocompatibility and …
Strategies for delivering nanoparticles across tumor blood vessels
Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …
Nanoparticle surface engineering with heparosan polysaccharide reduces serum protein adsorption and enhances cellular uptake
Nanoparticle modification with poly (ethylene glycol)(PEG) is a widely used surface
engineering strategy in nanomedicine. However, since the artificial PEG polymer may …
engineering strategy in nanomedicine. However, since the artificial PEG polymer may …
Engineering at the nano-bio interface: harnessing the protein corona towards nanoparticle design and function
Unpredictable and uncontrollable protein adsorption on nanoparticles remains a
considerable challenge to achieving effective application of nanotechnologies within …
considerable challenge to achieving effective application of nanotechnologies within …
Exploring and analyzing the systemic delivery barriers for nanoparticles
L Wang, S Quine, AN Frickenstein… - Advanced Functional …, 2024 - Wiley Online Library
Most nanomedicines require efficient in vivo delivery to elicit meaningful diagnostic and
therapeutic effects. However, en route to their intended tissues, systemically administered …
therapeutic effects. However, en route to their intended tissues, systemically administered …
Quantifying intracellular nanoparticle distributions with three-dimensional super-resolution microscopy
Super-resolution microscopy can transform our understanding of nanoparticle–cell
interactions. Here, we established a super-resolution imaging technology to visualize …
interactions. Here, we established a super-resolution imaging technology to visualize …
Controlling nanoparticle uptake in innate immune cells with heparosan polysaccharides
We used heparosan (HEP) polysaccharides for controlling nanoparticle delivery to innate
immune cells. Our results show that HEP-coated nanoparticles were endocytosed in a time …
immune cells. Our results show that HEP-coated nanoparticles were endocytosed in a time …
Quantification of monodisperse and biocompatible gold nanoparticles by single-particle ICP-MS
AN Frickenstein, S Mukherjee, T Harcourt, Y He… - Analytical and …, 2023 - Springer
Bioanalytical and biomedical applications often require nanoparticles that exhibit narrow
size distributions and biocompatibility. Here, we demonstrate how different synthesis …
size distributions and biocompatibility. Here, we demonstrate how different synthesis …
Lipid-mediated ex vivo cell surface engineering for augmented cellular functionalities
Once administrated, intercellular adhesion to recognize and/or arrest target cells is essential
for specific treatments, especially for cancer or tumor. However, immune cells administrated …
for specific treatments, especially for cancer or tumor. However, immune cells administrated …