Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L. towards future medicine
S Idris, A Mishra, M Khushtar - … of Basic and Clinical Physiology and …, 2020 - degruyter.com
Medicinal plants are used from ancient times for treatment of various ailments. Aesculus
hippocastanum (Horse chestnut), is the popular and most valuable tree native to the South …
hippocastanum (Horse chestnut), is the popular and most valuable tree native to the South …
Neuroinflammation in Parkinson's disease animal models: a cell stress response or a step in neurodegeneration?
C Cebrián, JD Loike, D Sulzer - Behavioral Neurobiology of Huntington's …, 2015 - Springer
The motor symptoms of Parkinson's disease are due to the progressive degeneration of
dopaminergic neurons in the substantia nigra. Multiple neuroinflammatory processes are …
dopaminergic neurons in the substantia nigra. Multiple neuroinflammatory processes are …
Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease
Q Zhang, Y Heng, Z Mou, J Huang, Y Yuan… - Acta pharmacologica …, 2017 - nature.com
Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) mouse model remains the most
commonly used animal model of Parkinson's disease (PD). There are three MPTP-treatment …
commonly used animal model of Parkinson's disease (PD). There are three MPTP-treatment …
Neuroprotective effect of lycopene against MPTP induced experimental Parkinson's disease in mice
Parkinson's disease (PD) is the second most common neurodegenerative disorder that
mainly affects the movement of the aged populations. Lycopene is a carotenoid with unique …
mainly affects the movement of the aged populations. Lycopene is a carotenoid with unique …
Lutein protects dopaminergic neurons against MPTP-induced apoptotic death and motor dysfunction by ameliorating mitochondrial disruption and oxidative stress
J Nataraj, T Manivasagam, AJ Thenmozhi… - Nutritional …, 2016 - Taylor & Francis
Objective: Mitochondrial dysfunction and oxidative stress-mediated apoptosis plays an
important role in various neurodegenerative diseases including Huntington's disease …
important role in various neurodegenerative diseases including Huntington's disease …
Ginkgo biloba protects striatal neurodegeneration and gut phagoinflammatory damage in rotenone‐induced mice model of Parkinson's disease: Role of executioner …
Asymptomatic and early clinical stages of Parkinson's disease (PD) have been linked with
comorbid non‐motor symptoms including dysfunction of the gastrointestinal (GI) tract …
comorbid non‐motor symptoms including dysfunction of the gastrointestinal (GI) tract …
Protective effect of curcumin against oxidative stress-induced injury in rats with Parkinson's disease through the Wnt/β-catenin signaling pathway
YL Wang, B Ju, YZ Zhang, HL Yin, YJ Liu… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: The study aimed to investigate the protective effect of curcumin against
oxidative stress-induced injury of Parkinson's disease (PD) through the Wnt/β-catenin …
oxidative stress-induced injury of Parkinson's disease (PD) through the Wnt/β-catenin …
Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein …
Y Heng, QS Zhang, Z Mu, JF Hu, YH Yuan, NH Chen - Toxicology Letters, 2016 - Elsevier
Parkinson's disease (PD) is pathologically characterized by the progressive loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation …
dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation …
Catalpol exerts a neuroprotective effect in the MPTP mouse model of Parkinson's disease
LY Wang, X Yu, XX Li, YN Zhao, CY Wang… - Frontiers in Aging …, 2019 - frontiersin.org
The degeneration of dopaminergic (DA) neurons in Parkinson's disease (PD) is related to
inflammation and oxidative stress. Anti-inflammatory agents could reduce the risk or slow the …
inflammation and oxidative stress. Anti-inflammatory agents could reduce the risk or slow the …
Neurotrophic Effect of Asiatic acid, a Triterpene of Centella asiatica Against Chronic 1-Methyl 4-Phenyl 1, 2, 3, 6-Tetrahydropyridine Hydrochloride/Probenecid Mouse …
J Nataraj, T Manivasagam, A Justin Thenmozhi… - Neurochemical …, 2017 - Springer
Regulation of various signalling (Ras-MAPK, PI3K and AKT) pathways by augmented
activity of neurotrophic factors (NTFs) could prevent or halt the progress of dopaminergic …
activity of neurotrophic factors (NTFs) could prevent or halt the progress of dopaminergic …