Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

Abstract microRNAs (miRNAs) are non-coding RNAs which have the capacity to regulate
gene expression at the post-transcriptional level, and have emerging as key factors involved …

Background: Osteosarcoma is the most common primary malignant bone tumour,
predominantly affecting children and adolescents. Cancer cell line models are required to …

Abstract miR-18a is a member of primary transcript called miR-17-92a (C13orf25 or
MIR17HG) which also contains five other miRNAs: miR-17, miR-19a, miR-20a, miR-19b and …

MicroRNAs (miRNAs) are endogenous, non-coding, single-stranded small RNAs involved in
a variety of cellular processes, including ontogeny, cell proliferation, differentiation, and …

Osteosarcoma is the most common primary malignancy of bone, typically presenting in the
first or second decade of life. Unfortunately, clinical outcomes for osteosarcoma patients …

Cancer cells usually utilize glucose as a carbon source for aerobic glycolysis, a
phenomenon known as the Warburg effect. Increasing studies have shown that PVT1 (a …

MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

Osteosarcoma is the most common bone cancer in children and young adults. Surgery and
multi-agent chemotherapy are the standard treatment regimens for this disease. New …

MicroRNA (miRNA) has shown to enhance or inhibit cell proliferation, differentiation and
activity of different cell types in bone tissue. The discovery of miRNA actions and their targets …