NDM metallo-β-lactamases and their bacterial producers in health care settings
W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …
Infections Caused by Carbapenem-Resistant Enterobacteriaceae: An Update on Therapeutic Options
CC Sheu, YT Chang, SY Lin, YH Chen… - Frontiers in …, 2019 - frontiersin.org
Carbapenems are considered as last-resort antibiotics for the treatment of infections caused
by multidrug-resistant Gram-negative bacteria. With the increasing use of carbapenems in …
by multidrug-resistant Gram-negative bacteria. With the increasing use of carbapenems in …
Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae
J Rodríguez-Baño, B Gutiérrez-Gutiérrez… - Clinical microbiology …, 2018 - Am Soc Microbiol
Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …
challenging, and some of the few active drugs are not available in many countries. For …
Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence …
Background The prevalence and effects of inappropriate empirical antibiotic therapy for
bloodstream infections are unclear. We aimed to establish the population-level burden …
bloodstream infections are unclear. We aimed to establish the population-level burden …
Effect of appropriate combination therapy on mortality of patients with bloodstream infections due to carbapenemase-producing Enterobacteriaceae (INCREMENT): a …
B Gutiérrez-Gutiérrez, E Salamanca… - The Lancet Infectious …, 2017 - thelancet.com
Background The best available treatment against carbapenemase-producing
Enterobacteriaceae (CPE) is unknown. The objective of this study was to investigate the …
Enterobacteriaceae (CPE) is unknown. The objective of this study was to investigate the …
Phenotypic and Genotypic Characterization of Carbapenem-resistant Enterobacteriaceae: Data From a Longitudinal Large-scale CRE Study in China (2012–2016)
Q Wang, X Wang, J Wang, P Ouyang… - Clinical Infectious …, 2018 - academic.oup.com
Abstract Background Carbapenem-resistant Enterobacteriaceae (CRE) strains are a major
threat to global health. The development of effective control measures requires more …
threat to global health. The development of effective control measures requires more …
Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study
M Tumbarello, EM Trecarichi… - Journal of …, 2015 - academic.oup.com
Abstract Objectives Infections caused by Klebsiella pneumoniae (Kp) carbapenemase
(KPC)-producing strains of Kp have become a significant threat in recent years. To assess …
(KPC)-producing strains of Kp have become a significant threat in recent years. To assess …
Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems
GL Daikos, S Tsaousi, LS Tzouvelekis… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Carbapenemase-producing Klebsiella pneumoniae strains (CP-Kps) are currently among
the most important nosocomial pathogens. An observational study was conducted during …
the most important nosocomial pathogens. An observational study was conducted during …
Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase–Producing K. pneumoniae: Importance of Combination …
M Tumbarello, P Viale, C Viscoli… - Clinical infectious …, 2012 - academic.oup.com
Abstract Background. The spread of Klebsiella pneumoniae (Kp) strains that produce K.
pneumoniae carbapenemases (KPCs) has become a significant problem, and treatment of …
pneumoniae carbapenemases (KPCs) has become a significant problem, and treatment of …
Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions
LS Tzouvelekis, A Markogiannakis… - Clinical microbiology …, 2012 - Am Soc Microbiol
The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …