The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

Background Supplemental oxygen is often administered liberally to acutely ill adults, but the
credibility of the evidence for this practice is unclear. We systematically reviewed the efficacy …

Importance The administration of a high fraction of oxygen following return of spontaneous
circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. Objective …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Importance Despite suggestions of potential harm from unnecessary oxygen therapy,
critically ill patients spend substantial periods in a hyperoxemic state. A strategy of controlled …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

BTS guideline for oxygen use in adults in healthcare and emergency settings | Thorax Skip to
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Background There is insufficient research into the use of mechanical ventilation with
increased inspiratory oxygen concentration (FiO 2) and fluid resuscitation with hypertonic …

Objective: Oxygen is vital during critical illness, but hyperoxia may harm patients. Our aim
was to systematically evaluate the methodology and findings of cohort studies investigating …

Rationale: There are no randomized controlled trials comparing different oxygenation
targets for intensive care unit (ICU) patients. Objectives: To determine whether a …