Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

[HTML][HTML] Bacterial biofilm eradication agents: a current review

AD Verderosa, M Totsika, KE Fairfull-Smith - Frontiers in chemistry, 2019 - frontiersin.org
Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

N Kayagaki, IB Stowe, BL Lee, K O'Rourke… - Nature, 2015 - nature.com
Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli,
Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse …

[HTML][HTML] Reassessing the host defense peptide landscape

EF Haney, SK Straus, REW Hancock - Frontiers in chemistry, 2019 - frontiersin.org
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

[HTML][HTML] Antimicrobial peptides

L Zhang, RL Gallo - Current biology, 2016 - cell.com
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Intracellular targeting mechanisms by antimicrobial peptides

CF Le, CM Fang, SD Sekaran - Antimicrobial agents and …, 2017 - Am Soc Microbiol
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host
defenses against potential harmful encounters in their surroundings. AMPs are short …

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

JM Ageitos, A Sánchez-Pérez, P Calo-Mata… - Biochemical …, 2017 - Elsevier
Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

Antimicrobial drug resistance in poultry production: current status and innovative strategies for bacterial control

R Abreu, T Semedo-Lemsaddek, E Cunha, L Tavares… - Microorganisms, 2023 - mdpi.com
The world population's significant increase has promoted a higher consumption of poultry
products, which must meet the specified demand while maintaining their quality and safety. It …

Antimicrobial peptides: a new frontier in antifungal therapy

G Buda De Cesare, SA Cristy, DA Garsin, MC Lorenz - MBio, 2020 - Am Soc Microbiol
Invasive fungal infections in humans are generally associated with high mortality, making
the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of …