Circuit organization of the rodent medial prefrontal cortex
PG Anastasiades, AG Carter - Trends in neurosciences, 2021 - cell.com
The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
CB Klune, B Jin, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …
play key roles in memory, cognition, decision making, social behaviors, and mood …
Deep self-learning enables fast, high-fidelity isotropic resolution restoration for volumetric fluorescence microscopy
K Ning, B Lu, X Wang, X Zhang, S Nie, T Jiang… - Light: Science & …, 2023 - nature.com
One intrinsic yet critical issue that troubles the field of fluorescence microscopy ever since its
introduction is the unmatched resolution in the lateral and axial directions (ie, resolution …
introduction is the unmatched resolution in the lateral and axial directions (ie, resolution …
High-definition imaging using line-illumination modulation microscopy
Q Zhong, A Li, R Jin, D Zhang, X Li, X Jia, Z Ding… - Nature …, 2021 - nature.com
The microscopic visualization of large-scale three-dimensional (3D) samples by optical
microscopy requires overcoming challenges in imaging quality and speed and in big data …
microscopy requires overcoming challenges in imaging quality and speed and in big data …
Distinct projections from the infralimbic cortex exert opposing effects in modulating anxiety and fear
YH Chen, JL Wu, NY Hu, JP Zhuang… - The Journal of …, 2021 - Am Soc Clin Investig
Anxiety-related disorders can be treated by cognitive therapies and transcranial magnetic
stimulation, which involve the medial prefrontal cortex (mPFC). Subregions of the mPFC …
stimulation, which involve the medial prefrontal cortex (mPFC). Subregions of the mPFC …
Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer's disease
Short-term memory deficits have been associated with prefrontal cortex (PFC) dysfunction in
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …
Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …
Mediodorsal and ventromedial thalamus engage distinct L1 circuits in the prefrontal cortex
Interactions between the thalamus and prefrontal cortex (PFC) play a critical role in cognitive
function and arousal. Here, we use anatomical tracing, electrophysiology, optogenetics, and …
function and arousal. Here, we use anatomical tracing, electrophysiology, optogenetics, and …
Molecularly defined and functionally distinct cholinergic subnetworks
X Li, H Yu, B Zhang, L Li, W Chen, Q Yu, X Huang… - Neuron, 2022 - cell.com
Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …
input to the forebrain and modulate diverse functions, including sensory processing …
Neuromodulation of hippocampal-prefrontal cortical synaptic plasticity and functional connectivity: implications for neuropsychiatric disorders
The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …
executive and emotional functions. Neurophysiological studies have begun to unveil the …