The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …

The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …

One intrinsic yet critical issue that troubles the field of fluorescence microscopy ever since its
introduction is the unmatched resolution in the lateral and axial directions (ie, resolution …

The microscopic visualization of large-scale three-dimensional (3D) samples by optical
microscopy requires overcoming challenges in imaging quality and speed and in big data …

Anxiety-related disorders can be treated by cognitive therapies and transcranial magnetic
stimulation, which involve the medial prefrontal cortex (mPFC). Subregions of the mPFC …

Short-term memory deficits have been associated with prefrontal cortex (PFC) dysfunction in
Alzheimer's disease (AD) and AD mouse models. Extratelencephalic projection (ET) …

Social competition plays a pivotal role in determining individuals' social status. While the
dorsomedial prefrontal cortex (dmPFC) is essential in regulating social competition, it …

Interactions between the thalamus and prefrontal cortex (PFC) play a critical role in cognitive
function and arousal. Here, we use anatomical tracing, electrophysiology, optogenetics, and …

Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …

The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …