[HTML][HTML] Inflammation, oxidative stress, and obesity

A Fernández-Sánchez, E Madrigal-Santillán… - International journal of …, 2011 - mdpi.com
Obesity is a chronic disease of multifactorial origin and can be defined as an increase in the
accumulation of body fat. Adipose tissue is not only a triglyceride storage organ, but studies …

Inflammation-induced thrombosis: mechanisms, disease associations and management

K Aksu, A Donmez, G Keser - Current pharmaceutical design, 2012 - ingentaconnect.com
Although inflammation-induced thrombosis is a well-known entity, its pathogenesis remains
complicated. There are complex interactions between inflammation and hemostasis …

Platelet activation in obesity and metabolic syndrome

F Santilli, N Vazzana, R Liani, MT Guagnano… - Obesity …, 2012 - Wiley Online Library
Obesity is associated with increased cardiovascular disease. Metabolic syndrome (MS)
identifies substantial additional cardiovascular risk beyond the individual risk factors, and is …

The role of aspirin in cardiovascular prevention: implications of aspirin resistance

AY Gasparyan, T Watson, GYH Lip - Journal of the American College of …, 2008 - jacc.org
Aspirin is well recognized as an effective antiplatelet drug for secondary prevention in
subjects at high risk of cardiovascular events. However, most patients receiving long-term …

[HTML][HTML] Not all (N) SAID and done: Effects of nonsteroidal anti‐inflammatory drugs and paracetamol intake on platelets

B Driver, DC Marks, DE van der Wal - Research and Practice in Thrombosis …, 2020 - Elsevier
Platelets are key mediators of hemostasis and thrombosis and can be inhibited by
nonsteroidal anti‐inflammatory drugs (NSAIDs). As a result, platelet donors are temporarily …

[HTML][HTML] Association of serum paraoxonase enzyme activity and oxidative stress markers with dyslipidemia in obese adolescents

ME Zaki, H El-Bassyouni, S Kamal… - Indian journal of …, 2014 - journals.lww.com
Objectives: The aim of the present study was to investigate the serum paraoxonase 1
(PON1) concentration and oxidative stress markers and assess its relations with the …

Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-tereated healthy adult volunteers

B Cryer, RG Berlin, SA Cooper, C Hsu, S Wason - Clinical therapeutics, 2005 - Elsevier
BACKGROUND:: Patients taking aspirin for cardioprotection may occasionally take over-the-
counter (OTC) ibuprofen for pain relief, which might interfere with the antiplatelet effects of …

[HTML][HTML] Aspirin increases metabolism through germline signalling to extend the lifespan of Caenorhabditis elegans

XB Huang, XH Mu, QL Wan, XM He, GS Wu, HR Luo - PloS one, 2017 - journals.plos.org
Aspirin is a prototypic cyclooxygenase inhibitor with a variety of beneficial effects on human
health. It prevents age-related diseases and delays the aging process. Previous research …

Home pharmacological therapy in early COVID‐19 to prevent hospitalization and reduce mortality: time for a suitable proposal

S Pandolfi, S Chirumbolo, G Ricevuti… - Basic & Clinical …, 2022 - Wiley Online Library
The COVID‐19 pandemic is a highly dramatic concern for mankind. In Italy, the pandemic
exerted its major impact throughout the period of February to June 2020. To date, the …

High glucose inhibits the aspirin-induced activation of the nitric oxide/cGMP/cGMP-dependent protein kinase pathway and does not affect the aspirin-induced …

I Russo, M Viretto, C Barale, L Mattiello, G Doronzo… - Diabetes, 2012 - Am Diabetes Assoc
Since hyperglycemia is involved in the “aspirin resistance” occurring in diabetes, we aimed
at evaluating whether high glucose interferes with the aspirin-induced inhibition of …