Technologically critical rare-earth elements are notoriously difficult to separate, owing to
their subtle differences in ionic radius and coordination number,–. The natural lanthanide …

The extreme durability of polyethylene terephthalate (PET) debris has rendered it a long-
term environmental burden. At the same time, current recycling efforts still lack sustainability …

Methylation of adenosines at the N6 position (m6A) is a dynamic and abundant
epitranscriptomic mark that regulates critical aspects of eukaryotic RNA metabolism in …

Transient receptor potential (TRP) channels are a large, eukaryotic ion channel superfamily
that control diverse physiological functions, and therefore are attractive drug targets,,,–. More …

T cells discriminate between foreign and host molecules by recognizing distinct microbial
molecules, predominantly peptides and lipids,,,. Riboflavin precursors found in many …

Leukotrienes (LT) are lipid mediators of the inflammatory response that are linked to asthma
and atherosclerosis. LT biosynthesis is initiated by 5-lipoxygenase (5-LOX) with the …

Antigen-presenting molecules, encoded by the major histocompatibility complex (MHC) and
CD1 family, bind peptide-and lipid-based antigens, respectively, for recognition by T cells …

Introduction Bacteria and archaea defend themselves against invasive DNA using adaptive
immune systems comprising CRISPR (clustered regularly interspaced short palindromic …

Mucosal-associated invariant T cells (MAIT cells) express a semi-invariant T cell receptor
(TCR) α-chain, TRAV1-2–TRAJ33, and are activated by vitamin B metabolites bound by the …

Protein X-ray crystallography recently celebrated its 50th anniversary. The structures of
myoglobin and hemoglobin determined by Kendrew and Perutz provided the first glimpses …