Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …

Obesity, manifested by increased adiposity, represents a main cause of morbidity in the
developed countries, causing increased risk of insulin resistance and type 2 diabetes …

Mitochondria are important regulators of macrophage polarisation. Here, we show that
arginase-2 (Arg2) is a microRNA-155 (miR-155) and interleukin-10 (IL-10) regulated protein …

Obesity is characterized by a state of chronic inflammation in adipose tissue mediated by the
secretion of a range of inflammatory cytokines. In comparison to WAT, relatively little is …

Obesity is considered to significantly increase the risk of the development of a vast range of
metabolic diseases. However, adipogenesis is a complex physiological process, necessary …

Mitochondria are required for energy production and even give brown adipose tissue (BAT)
its characteristic color due to their high iron content and abundance. The physiological …

Mitochondrial temperature is produced by various metabolic processes inside the
mitochondria, particularly oxidative phosphorylation. It was recently reported that …

Background Exercise is an important strategy in the management of diabetes. Experimental
studies have shown that exercise acts, at least in part, by inducing the production of …

Alzheimer's disease (AD) is a leading cause of cognitive impairment worldwide. Overweight
and obesity are strongly associated with comorbidities, such as hypertension, diabetes, and …

Brown adipose tissue (BAT), a crucial heat-generating organ, regulates whole-body energy
metabolism by mediating thermogenesis. BAT inflammation is implicated in the …