Accelerating crop genetic gains with genomic selection
Key message Genomic prediction based on additive genetic effects can accelerate genetic
gain. There are opportunities for further improvement by including non-additive effects that …
gain. There are opportunities for further improvement by including non-additive effects that …
Ecological genomics of local adaptation
It is increasingly important to improve our understanding of the genetic basis of local
adaptation because of its relevance to climate change, crop and animal production, and …
adaptation because of its relevance to climate change, crop and animal production, and …
Functional mapping and annotation of genetic associations with FUMA
K Watanabe, E Taskesen, A Van Bochoven… - Nature …, 2017 - nature.com
A main challenge in genome-wide association studies (GWAS) is to pinpoint possible causal
variants. Results from GWAS typically do not directly translate into causal variants because …
variants. Results from GWAS typically do not directly translate into causal variants because …
Breeding crops for drought-affected environments and improved climate resilience
M Cooper, CD Messina - The Plant Cell, 2023 - academic.oup.com
Breeding climate-resilient crops with improved levels of abiotic and biotic stress resistance
as a response to climate change presents both opportunities and challenges. Applying the …
as a response to climate change presents both opportunities and challenges. Applying the …
Enhancing genetic gain through genomic selection: from livestock to plants
Although long-term genetic gain has been achieved through increasing use of modern
breeding methods and technologies, the rate of genetic gain needs to be accelerated to …
breeding methods and technologies, the rate of genetic gain needs to be accelerated to …
Promises and challenges of big data computing in health sciences
With the development of smart devices and cloud computing, more and more public health
data can be collected from various sources and can be analyzed in an unprecedented way …
data can be collected from various sources and can be analyzed in an unprecedented way …
Predicting the future of plant breeding: complementing empirical evaluation with genetic prediction
M Cooper, CD Messina, D Podlich… - Crop and Pasture …, 2014 - CSIRO Publishing
For the foreseeable future, plant breeding methodology will continue to unfold as a practical
application of the scaling of quantitative biology. These efforts to increase the effective scale …
application of the scaling of quantitative biology. These efforts to increase the effective scale …
The genetic epidemiology of substance use disorder: A review
EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …
greater understanding of how genes and environment interact to regulate phenotypes …
Integrating crop growth models with whole genome prediction through approximate Bayesian computation
Genomic selection, enabled by whole genome prediction (WGP) methods, is revolutionizing
plant breeding. Existing WGP methods have been shown to deliver accurate predictions in …
plant breeding. Existing WGP methods have been shown to deliver accurate predictions in …
Leveraging biological insight and environmental variation to improve phenotypic prediction: Integrating crop growth models (CGM) with whole genome prediction …
A successful strategy for prediction of crop yield that accounts for the effects of genotype,
environment and their interactions with management will create many opportunities for …
environment and their interactions with management will create many opportunities for …