Management of rheumatoid arthritis: an overview

AF Radu, SG Bungau - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology,
primarily affecting the joints, then extra-articular manifestations can occur. Due to its …

Methotrexate and its mechanisms of action in inflammatory arthritis

BN Cronstein, TM Aune - Nature Reviews Rheumatology, 2020 - nature.com
Despite the introduction of numerous biologic agents for the treatment of rheumatoid arthritis
(RA) and other forms of inflammatory arthritis, low-dose methotrexate therapy remains the …

2021 American College of Rheumatology guideline for the treatment of rheumatoid arthritis

L Fraenkel, JM Bathon, BR England… - Arthritis & …, 2021 - Wiley Online Library
Objective To develop updated guidelines for the pharmacologic management of rheumatoid
arthritis. Methods We developed clinically relevant population, intervention, comparator, and …

Effect of immunosuppression on the immunogenicity of mRNA vaccines to SARS-CoV-2: a prospective cohort study

P Deepak, W Kim, MA Paley, M Yang… - Annals of internal …, 2021 - acpjournals.org
Background: Patients with chronic inflammatory disease (CID) treated with
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …

American College of Rheumatology guidance for COVID‐19 vaccination in patients with rheumatic and musculoskeletal diseases: version 2

JR Curtis, SR Johnson, DD Anthony… - Arthritis & …, 2021 - Wiley Online Library
Objective To provide guidance to rheumatology providers on the use of coronavirus disease
2019 (COVID‐19) vaccines for patients with rheumatic and musculoskeletal diseases …

EULAR definition of difficult-to-treat rheumatoid arthritis

G Nagy, NMT Roodenrijs, PMJ Welsing… - Annals of the …, 2021 - ard.bmj.com
Background Despite treatment according to the current management recommendations, a
significant proportion of patients with rheumatoid arthritis (RA) remain symptomatic. These …

Surgical and tissue engineering strategies for articular cartilage and meniscus repair

H Kwon, WE Brown, CA Lee, D Wang… - Nature Reviews …, 2019 - nature.com
Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately
results in arthritis. Different forms of arthritis affect~ 50 million people in the USA alone, and it …

EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis

G Nagy, NMT Roodenrijs, PMJ Welsing… - Annals of the …, 2022 - ard.bmj.com
Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

[HTML][HTML] Global, regional, and national burden of rheumatoid arthritis, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease …

RJ Black, M Cross, LM Haile, GT Culbreth… - The Lancet …, 2023 - Elsevier
Background Rheumatoid arthritis is a chronic autoimmune inflammatory disease associated
with disability and premature death. Up-to-date estimates of the burden of rheumatoid …

Diagnosis and management of rheumatoid arthritis: a review

D Aletaha, JS Smolen - Jama, 2018 - jamanetwork.com
Importance Rheumatoid arthritis (RA) occurs in about 5 per 1000 people and can lead to
severe joint damage and disability. Significant progress has been made over the past 2 …