Ischaemia‐reperfusion injury is a complex phenomenon often encountered in surgical
practice. The consequences of such injury are local and remote tissue destruction, and …

Background: Myocardial ischemia–reperfusion represents a clinically relevant problem
associated with thrombolysis, angioplasty and coronary bypass surgery. Injury of …

BACKGROUND To test the hypothesis that the heat shock response is associated with
myocardial salvage, the heat stress protein (HSP) content of cardiac tissue was increased by …

How a cell responds to stress is a central problem in cardiovascular biology. Diverse
physiological stresses (eg, heat, hemodynamics, mutant proteins, and oxidative injury) …

The infarct-limiting effect of ischemic preconditioning is believed to be a transient
phenomenon. We examined the delayed effects of repetitive brief ischemia on limiting infarct …

Tufts University School of Medicine one liter/day. On day 13, the BUN was 78 mg/dl and the
serum creatinine was 3.5 mg/dl. A blood culture grew methicillin-resistant Staphylococcus …

Myocardial protection and changes in gene expression follow whole body heat stress.
Circumstantial evidence suggests that an inducible 70-kD heat shock protein (hsp70i) …

In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself
against external stressors from various sources. This defense mechanism probably evolved …

The heat shock proteins (hsps) are expressed in normal cells but their expression is
enhanced by a number of different stresses including heat and ischaemia. They play …

The accumulation of misfolded proteins in the cytosol leads to increased expression of heat-
shock proteins, while accumulation of such proteins in the endoplasmic reticulum (ER) …