Advances in hydrogen/deuterium exchange mass spectrometry and the pursuit of challenging biological systems
EI James, TA Murphree, C Vorauer, JR Engen… - Chemical …, 2021 - ACS Publications
Solution-phase hydrogen/deuterium exchange (HDX) coupled to mass spectrometry (MS) is
a widespread tool for structural analysis across academia and the biopharmaceutical …
a widespread tool for structural analysis across academia and the biopharmaceutical …
Developments in hydrogen/deuterium exchange mass spectrometry
Chemistry” on HDX MS. 1 That review covered HDX MS applications from January 2012
through June 2014 and described the publications in terms of sector, geography, and topic …
through June 2014 and described the publications in terms of sector, geography, and topic …
[HTML][HTML] SRPK1/2 and PP1α exert opposite functions by modulating SRSF1-guided MKNK2 alternative splicing in colon adenocarcinoma
Abstract Background The Mnk2 kinase, encoded by MKNK2 gene, plays critical roles in
MAPK signaling and was involved in oncogenesis. Human MKNK2 pre-mRNA can be …
MAPK signaling and was involved in oncogenesis. Human MKNK2 pre-mRNA can be …
Subsecond time-resolved mass spectrometry in dynamic structural biology
C Lento, DJ Wilson - Chemical Reviews, 2021 - ACS Publications
Life at the molecular level is a dynamic world, where the key players─ proteins,
oligonucleotides, lipids, and carbohydrates─ are in a perpetual state of structural flux …
oligonucleotides, lipids, and carbohydrates─ are in a perpetual state of structural flux …
[HTML][HTML] Overview of protein posttranslational modifications in Arthropoda venoms
MN Melo-Braga, RS Moreira, JHDB Gervásio… - Journal of Venomous …, 2022 - SciELO Brasil
Accidents with venomous animals are a public health issue worldwide. Among the species
involved in these accidents are scorpions, spiders, bees, wasps, and other members of the …
involved in these accidents are scorpions, spiders, bees, wasps, and other members of the …
[HTML][HTML] Proteogenomic Approaches to Understand Gene Mutations and Protein Structural Alterations in Colon Cancer
S Sarkar - Physiologia, 2023 - mdpi.com
With colon cancer being one of the deadliest and most common cancers, understanding the
mechanisms behind colon cancer is crucial in improving therapies. One of the newest …
mechanisms behind colon cancer is crucial in improving therapies. One of the newest …
[HTML][HTML] The mechanism of USP43 in the development of tumor: a literature review
Z Zhao, M Liu, Z Lin, M Zhu, L Lv, X Zhu, R Fan… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Ubiquitination of the proteins is crucial for governing protein degradation and regulating
fundamental cellular processes. Deubiquitinases (DUBs) have emerged as significant …
fundamental cellular processes. Deubiquitinases (DUBs) have emerged as significant …
Prognostic value and oncogenic effects of ubiquitin-specific protease 43 in lung squamous cell carcinoma
Q Sun, H Zhang, L Zong, A Julaiti, X Jing… - The Tohoku Journal of …, 2022 - jstage.jst.go.jp
Dysregulated expression of ubiquitin-specific protease 43 (USP43) has been recently
discovered in malignancies. This study aimed to investigate the expression pattern of …
discovered in malignancies. This study aimed to investigate the expression pattern of …
The molecular sociology of NHERF1 PDZ proteins controlling renal hormone-regulated phosphate transport
T Mamonova, PA Friedman - Bioscience Reports, 2024 - portlandpress.com
Parathyroid hormone (PTH) and fibroblast growth factor-23 (FGF23) control extracellular
phosphate levels by regulating renal NPT2A-mediated phosphate transport by a process …
phosphate levels by regulating renal NPT2A-mediated phosphate transport by a process …
tRNA‐Uridine Aminocarboxypropyltransferase DTW Domain Containing 2 Suppresses Colon Adenocarcinoma Progression
Y Qian, YJ Li, YW Fu, CX Liu, J Wang… - International Journal of …, 2023 - Wiley Online Library
Background. DTW Domain Containing 2 (DTWD2) is a newly identified transfer RNA‐uridine
aminocarboxypropyltransferase. Dysregulated expression of DTWD1 has been reported in …
aminocarboxypropyltransferase. Dysregulated expression of DTWD1 has been reported in …