Deciphering the potential therapeutic effects of Hydnocarpus wightianus seed extracts using in vitro and in silico approaches

N Kathiresan, K Harini, P Veerabharathi, S Pandi… - Microbial …, 2024 - Elsevier
Phytocompounds possess the potential to treat a broad spectrum of disorders due to their
remarkable bioactivity. Naturally occurring compounds possess lower toxicity profiles, which …

Understanding the Pharmacological and Nanotechnological Facets of Dipeptidyl Peptidase-4 Inhibitors in Type II Diabetes Mellitus: a Paradigm in Therapeutics

N Tiwary, N Sharma, S Singh, T Behl, I Zahoor - BioNanoScience, 2024 - Springer
The worldwide incidence of type 2 diabetes mellitus (T2DM), a chronic metabolic disorder, is
increasing rapidly. A newer category of oral hypoglycemic medications called dipeptidyl …

Genotypic Analysis of COL4A1 Gene in Diabetic Nephropathy and Type 2 Diabetes Mellitus Patients: A Comparative Genetic Study

N Shukla, S Kumari, P Verma, AS Kushwah… - DNA and Cell …, 2023 - liebertpub.com
Diabetic nephropathy (DN) is specified by microalbuminuria, glomerular lesions, and renal
fibrosis leading to end-stage renal disease. The pathophysiology of DN is multifactorial as a …

Discovery of Novel and Selective Schiff Base Inhibitors as a Key for Drug Synthesis, Molecular Docking, and Pharmacological Evaluation

I Khan, W Rehman, L Rasheed, F Rahim, R Hussain… - ACS …, 2024 - ACS Publications
Diabetes mellitus (DM) is a chronic disorder and still a challenge throughout the world, and
therefore the search for safe and effective inhibitors for α-amylase and α-glucosidase is …

Computational Approaches to Elucidate the Mechanism of Serine–Threonine Kinase (AKT1) Inhibition by Streptococcus pyogenes Exotoxin Superantigen‐Derived …

N Kathiresan, P Jayaprakash… - Peptide Science, 2024 - Wiley Online Library
ABSTRACT A serine–threonine kinase 1 (AKT1) plays a significant role in biological
processes, including cell division, survival, glucose metabolism, and apoptosis pathway. It …

Diabetes Treatment and Prevention Using Herbal Medicine

BO Yusuf, RA Abdulsalam, S Sabiu - Herbal Medicine Phytochemistry …, 2023 - Springer
Diabetes is a cluster of prevalent hormonal conditions that display abnormally high blood
glucose level. Diabetes is caused by the improper utilization of insulin by body cells or …

A Comparative Study of Mean Platelet Volume in Diabetic Population With and Without Vascular Complication

AS Vasudhevan, DM Sumathi… - … Journal of Medical …, 2023 - journal2.unusa.ac.id
Diabetes mellitus leads to long-term complications involving multiple organs and systems of
the human body. Among the list of complications, a relatively vascular complication …

[引用][C] Diabetes mellitus impact on oral health: Insights into cancer risk and beyond

K Langeswaran, R Sangeetha - Oral Oncology Reports, 2024 - Elsevier