Regulation of H2O2-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes

B Saberi, M Shinohara, MD Ybanez… - … of Physiology-Cell …, 2008 - journals.physiology.org
Recent studies have suggested that, in certain cases, necrosis, like apoptosis, may be
programmed, involving the activation and inhibition of many signaling pathways. In this …

Poly (ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts

HZ Zhou, RA Swanson, U Simonis… - American Journal …, 2006 - journals.physiology.org
Poly (ADP-ribose) polymerase-1 (PARP-1), the most abundant member of the PARP family,
is a nuclear enzyme that catalyzes ADP-ribose transfer from NAD+ to specific acceptor …

Morphogenic protein epimorphin protects intestinal epithelial cells from oxidative stress by the activation of EGF receptor and MEK/ERK, PI3 kinase/Akt signals

M Iizuka, K Sasaki, Y Hirai, K Shindo… - American Journal …, 2007 - journals.physiology.org
Epimorphin is a mesenchymal protein that regulates morphogenesis of epithelial cells. Our
preliminary study suggested a novel function of epimorphin in enhancing survival of …

[PDF][PDF] XXX. ÉVF. 4. SZÁM 2006. DECEMBER

G PÁL, H FERENC, N LÁSZLÓ, S BALÁZS, S ANDRÁS - real-j.mtak.hu
According to the classical view, the cytoprotective effect of inhibitors of poly (ADP-ribose)
polymerase-1 (PARP) enzyme in oxidative stress was based on the prevention of NAD+ and …