Vascular smooth muscle remodeling in conductive and resistance arteries in hypertension
IAM Brown, L Diederich, ME Good… - … , and vascular biology, 2018 - Am Heart Assoc
Cardiovascular disease is a leading cause of death worldwide and accounts for> 17.3
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …
million deaths per year, with an estimated increase in incidence to 23.6 million by 2030 …
Arterial stiffness, systolic blood pressure, and logical treatment of arterial hypertension.
M O'Rourke - Hypertension, 1990 - Am Heart Assoc
Arterial stiffening is the principal cause of increasing systolic pressure with advancing years
and in patients with arterial hypertension. It is associated with progressive arterial dilation …
and in patients with arterial hypertension. It is associated with progressive arterial dilation …
Structural and genetic bases of arterial stiffness
Arterial stiffness has independent predictive value for cardiovascular events. We review data
concerning the heritability of arterial stiffness, and propose an integrated view of the …
concerning the heritability of arterial stiffness, and propose an integrated view of the …
Elastase-induced experimental aneurysms in rats.
S Anidjar, JL Salzmann, D Gentric, P Lagneau… - Circulation, 1990 - Am Heart Assoc
An experimental in vivo model of aortic aneurysm was established by perfusing an isolated
segment of rat abdominal aorta with pancreatic elastase. Ten rats were used in each …
segment of rat abdominal aorta with pancreatic elastase. Ten rats were used in each …
The effect of pressure-induced mechanical stretch on vascular wall differential gene expression
MA Anwar, J Shalhoub, CS Lim, MS Gohel… - Journal of vascular …, 2012 - karger.com
High blood pressure is responsible for the modulation of blood vessel morphology and
function. Arterial hypertension is considered to play a significant role in atherosclerotic …
function. Arterial hypertension is considered to play a significant role in atherosclerotic …
Cellular mechanics and gene expression in blood vessels
S Lehoux, A Tedgui - Journal of biomechanics, 2003 - Elsevier
Blood vessels are permanently subjected to mechanical forces in the form of stretch,
encompassing cyclic mechanical strain due to the pulsatile nature of blood flow, and shear …
encompassing cyclic mechanical strain due to the pulsatile nature of blood flow, and shear …
Angiotensin-converting enzyme and vascular remodeling
S Heeneman, JC Sluimer, MJAP Daemen - Circulation research, 2007 - Am Heart Assoc
Vascular remodeling is the result of a close interplay of changes in vascular tone and
structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of …
structure. In this review, the role of angiotension-converting enzyme (ACE) and the impact of …
Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells.
H Itoh, RE Pratt, VJ Dzau - The Journal of clinical …, 1990 - Am Soc Clin Investig
Vascular remodeling is central to the pathophysiology of hypertension and atherosclerosis.
Recent evidence suggests that vasoconstrictive substances, such as angiotensin II (AII), may …
Recent evidence suggests that vasoconstrictive substances, such as angiotensin II (AII), may …
Low‐pressure environment and remodelling of the forearm vein in Brescia–Cimino haemodialysis access
JM Corpataux, E Haesler, P Silacci… - Nephrology Dialysis …, 2002 - academic.oup.com
Background. The aim of the study was to determine which, and to what extent,
haemodynamic parameters contribute to the remodelling of the venous limb of the Brescia …
haemodynamic parameters contribute to the remodelling of the venous limb of the Brescia …
Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients
U Solzbach, B Hornig, M Jeserich, H Just - Circulation, 1997 - Am Heart Assoc
Background There is evidence for increased formation of free radicals in patients with
hypertension, raising the possibility that NO is inactivated by free radicals, which impairs …
hypertension, raising the possibility that NO is inactivated by free radicals, which impairs …